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DPA 714

Known as: DPA-714, DPA714 
National Institutes of Health

Papers overview

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2018
2018
Prolonged hematopoietic and myeloid cellular response in patients after an acute coronary syndrome measured with 18F-DPA-714 PET/CT
PurposeAn acute coronary syndrome (ACS) is characterized by a multi-level inflammatory response, comprising activation of bone… 
2017
2017
Evaluation of TSPO PET imaging, a marker of glial activation, to study the neuroimmune footprints of morphine exposure and withdrawal.
2017
2017
Evaluation of TSPO PET Ligands [18F]VUIIS1009A and [18F]VUIIS1009B: Tracers for Cancer Imaging
PurposePositron emission tomography (PET) ligands targeting translocator protein (TSPO) are potential imaging diagnostics of… 
2016
2016
Development of PET Imaging to Visualize Activated Macrophages Accumulated in the Transplanted iPSc-Derived Cardiac Myocytes of Allogeneic Origin for Detecting the Immune Rejection of Allogeneic Cell…
Allogeneic transplantation (Tx) of induced pluripotent stem cells (iPSCs) is a promising tissue regeneration therapy. However… 
Highly Cited
2015
Highly Cited
2015
In vivo imaging and characterization of [(18)F]DPA-714, a potential new TSPO ligand, in mouse brain and peripheral tissues using small-animal PET.
2015
2015
Longitudinal evaluation of glial activation after traumatic brain injury: 18F-DPA714 PET imaging in mice.
2014
2014
[18F]DPA-C5yne, a novel fluorine-18-labelled analogue of DPA-714: radiosynthesis and preliminary evaluation as a radiotracer for imaging neuroinflammation with PET.
DPA-C5yne, the lead compound of a novel series of DPA-714 derivatives in which the fluoroethoxy chain linked to the… 
2014
2014
Preparation and evaluation of novel pyrazolo[1,5-a]pyrimidine acetamides, closely related to DPA-714, as potent ligands for imaging the TSPO 18kDa with PET.
2013
2013
The Translocator Protein Radioligand 18F-DPA-714 Monitors Antitumor Effect of Erufosine in a Rat 9L Intracranial Glioma Model
On the one hand, the translocator protein (TSPO) radioligand N,N-diethyl-2-(2-(4-(2-18F-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo… 
Highly Cited
2012
Highly Cited
2012
Quantitative Preclinical Imaging of TSPO Expression in Glioma Using N,N-Diethyl-2-(2-(4-(2-18F-Fluoroethoxy)Phenyl)-5,7-Dimethylpyrazolo[1,5-a]Pyrimidin-3-yl)Acetamide
There is a critical need to develop and rigorously validate molecular imaging biomarkers to aid diagnosis and characterization of… 
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