DNA-methyltransferase activity

Known as: DNA transmethylase activity, deoxyribonucleate methylase activity, deoxyribonucleate methyltransferase activity 
Catalysis of the transfer of a methyl group to a DNA molecule. [GOC:jl, ISBN:0198506732]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2018
0102019732018

Papers overview

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Highly Cited
2007
Highly Cited
2007
Small DNA tumour viruses have evolved a number of mechanisms to drive nondividing cells into S phase. Virally encoded… (More)
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Highly Cited
2005
Highly Cited
2005
DNA methyltransferases have a central role in the complex regulatory network of epigenetic modifications controlling gene… (More)
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Highly Cited
2003
Highly Cited
2003
The DNA methyltransferases, Dnmts, are the enzymes responsible for methylating DNA in mammals, which leads to gene silencing… (More)
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Highly Cited
2003
Highly Cited
2003
During mammalian cell division, DNA methylation patterns are transferred accurately to the newly synthesized DNA strand. This… (More)
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Highly Cited
1996
Highly Cited
1996
The association between increased DNA-methyltransferase (DNA-MTase) activity and tumor development suggest a fundamental role for… (More)
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Highly Cited
1995
Highly Cited
1995
We have used a combination of genetics and pharmacology to assess the effects of reduced DNA methyltransferase activity on ApcMin… (More)
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Highly Cited
1993
Highly Cited
1993
The paternal and maternal genomes are not equivalent and both are required for mammalian development. The difference between the… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND Molecular changes during progressive stages of colon cancer and other human tumors commonly involve altered regulation… (More)
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Highly Cited
1992
Highly Cited
1992
Gene targeting in embryonic stem (ES) cells has been used to mutate the murine DNA methyltransferase gene. ES cell lines… (More)
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Highly Cited
1982
Highly Cited
1982
Treatment of Friend erythroleukemia cells with the antileukemic drugs 5-azacytidine and 5-aza-2'-deoxycytidine leads to rapid… (More)
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