DNA duplex unwinding

Known as: DNA unwinding, duplex DNA melting 
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands… (More)
National Institutes of Health

Papers overview

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2015
2015
The evolutionarily conserved G-quadruplexes (G4s) are faithfully inherited and serve a variety of cellular functions such as… (More)
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2013
2013
Single-molecule studies can overcome the complications of asynchrony and ensemble-averaging in bulk-phase measurements, provide… (More)
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2011
2011
AddAB is a helicase-nuclease that processes double-stranded DNA breaks for repair by homologous recombination. This process is… (More)
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2011
2011
The oligomeric state of Superfamily I DNA helicases is the subject of considerable and ongoing debate. While models based on… (More)
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Highly Cited
2007
Highly Cited
2007
Helicases are molecular motors that separate DNA strands for efficient replication of genomes. We probed the kinetics of… (More)
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Highly Cited
2004
Highly Cited
2004
We showed previously that rad50 and mre11 genes of thermophilic archaea are organized in an operon-like structure with a third… (More)
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Highly Cited
2003
Highly Cited
2003
Helicase-catalyzed DNA unwinding is often studied using "all or none" assays that detect only the final product of fully unwound… (More)
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2001
2001
E. coli Rep protein is a 3' to 5' SF1 superfamily DNA helicase which is monomeric in the absence of DNA, but can dimerize upon… (More)
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1995
1995
DNA helicases catalyze the unwinding of double-stranded (ds) DNA to yield the single-stranded (ss) DNA intermediates required in… (More)
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Review
1993
Review
1993
DNA helicases are ubiquitous and multiple helicases have been identified in a number of prokaryotes and eukaryotes. Although it… (More)
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