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DNA duplex unwinding

Known as: DNA unwinding, duplex DNA melting 
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Significance How ATP hydrolysis is coupled to promoter DNA unwinding and open complex formation at RNA polymerase II (Poll II… Expand
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Highly Cited
2013
Highly Cited
2013
Single-molecule studies can overcome the complications of asynchrony and ensemble-averaging in bulk-phase measurements, provide… Expand
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2008
2008
HCV NS3 helicase exhibits activity toward DNA and RNA substrates. The DNA helicase activity of NS3 has been proposed to be… Expand
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Highly Cited
2007
Highly Cited
2007
Helicases are molecular motors that separate DNA strands for efficient replication of genomes. We probed the kinetics of… Expand
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Highly Cited
2003
Highly Cited
2003
Helicase-catalyzed DNA unwinding is often studied using "all or none" assays that detect only the final product of fully unwound… Expand
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Highly Cited
2001
Highly Cited
2001
The minimal requirements for a eukaryotic origin of replication are an initiator binding site and a region of helically unstable… Expand
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Highly Cited
1997
Highly Cited
1997
Bacteriophage T7 DNA helicase requires two noncomplementary single-stranded DNA (ssDNA) tails next to a double-stranded DNA… Expand
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Highly Cited
1997
Highly Cited
1997
The bacteriophage T7 DNA helicase/primase (gene 4 protein) is a ring-like hexamer that encircles ssDNA and requires forked DNA to… Expand
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Review
1993
Review
1993
  • T. M. Lohman
  • The Journal of biological chemistry
  • 1993
  • Corpus ID: 15223388
DNA helicases are ubiquitous and multiple helicases have been identified in a number of prokaryotes and eukaryotes. Although it… Expand
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Highly Cited
1990
Highly Cited
1990
The nucleotide sequence of 6.2 kb (1 kb = 10(3) base-pairs) of DNA that encompasses the earliest replicating portion of the… Expand
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