DNA Minor Groove Binding

DNA Minor Groove Binding involves temporary non-covalent interaction through intermolecular physical forces of attraction by a protein or low… (More)
National Institutes of Health

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2013
2013
Derivatives of methyl 3-(1-methyl-5-(1-methyl-5-(propylcarbamoyl)-1H-pyrrol-3-ylcarbamoyl)-1H-pyrrol-3-ylamino)-3-oxopropane-1… (More)
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2013
2013
The effects of salt concentration and temperature on the thermodynamics of DNA minor groove binding have quite different… (More)
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2010
2010
Eight indole derivatives were studied for their DNA binding ability using fluorescence quenching and molecular docking methods… (More)
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2010
2010
The capacity of two minor groove binding agents that differ in their DNA sequence selectivity to modulate gene expression in… (More)
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2009
2009
Our previous work has shown that tanshinone IIA (Tan IIA) is a DNA minor groove binder instead of an intercalator as previously… (More)
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2002
2002
DNA minor groove binder hybrid molecules, netropsin derivatives such as N-[2-(dimethylamino)ethyl]-1-methyl-4-aminopyrrolo-2… (More)
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2002
2002
The synthesis of 1,3-bis-[3,4,5,6-tetrahydroxyazepane-N-p-phenoxy] and 1,3-bis-[3,4,5,6-tetrahydroxyazepane-N-p-benzyloxy… (More)
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2000
2000
Maintenance of genomic integrity is vital to all organisms. A number of human genetic disorders, including Werner Syndrome, Bloom… (More)
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2000
2000
Nitrogen mustards are commonly used in cancer chemotherapy. They interact with DNA at electronegative sites, primarily forming N7… (More)
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1998
1998
We have employed a broad range of spectroscopic, calorimetric, DNA cleavage, and DNA winding/unwinding measurements to… (More)
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