DNA Intrastrand Crosslinking

DNA Intrastrand Crosslinking involves the formation of a covalent bond between two bases on the same DNA strand. (NCI)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2017
02419852017

Papers overview

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2012
2012
Cisplatin (cis-diamminedichloroplatinum) and related compounds cause DNA damage and are widely used as anticancer agents… (More)
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2005
2005
Nucleotide excision repair (NER) plays an important role in maintaining the integrity of DNA by removing various types of bulky… (More)
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2000
2000
Mammalian chromosomes terminate with a 3' tail which consists of reiterations of the G-rich repeat, d(TTAGGG). The telomeric tail… (More)
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1999
1999
It is emerging that DNA tetraplexes are pivotal for many major cellular processes, and techniques that assess their structure and… (More)
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1997
1997
The antitumor agent cis-diamminedichloroplatinum(II) (cisplatin) introduces cytotoxic DNA damage predominantly in the form of… (More)
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Highly Cited
1995
Highly Cited
1995
THE success of cisplatin in cancer chemotherapy derives from its ability to crosslink DNA and alter the structure. Most cisplatin… (More)
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Highly Cited
1995
Highly Cited
1995
A large increase in the length of a CGG tandem array is associated with a number of triplet expansion diseases, including fragile… (More)
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1995
1995
The anticancer platinum compound cis-Pt(NH3)2Cl2 (cisplatin) forms covalent cross-linked adducts with DNA, with the intrastrand… (More)
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1992
1992
Human cDNA clones encoding a structure-specific recognition protein, SSRP1, that binds specifically to DNA modified with… (More)
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1986
1986
The antitumor activity of cis-diamminedichloroplatinum II (cisplatin) is believed to be related to its covalent interaction with… (More)
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