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DMP 696

Known as: 4-(1,3-dimethoxy-2-propylamino)-2,7-dimethyl-8-(2,4-dichlorophenyl)(1,5-a)pyrazolo-1,3,5-triazine, DMP-696, DMP696 
 
National Institutes of Health

Papers overview

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2012
2012
Persistent dreadful memories and hyperarousal constitute prominent psychopathological features of posttraumatic stress disorder… Expand
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Highly Cited
2007
Highly Cited
2007
Chronic stress is widely regarded as a key risk factor for a variety of diseases. A large number of paradigms have been used to… Expand
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Highly Cited
2007
Highly Cited
2007
The basolateral amygdala complex (BLA) and central amygdala nucleus (CeA) are involved in fear and anxiety. In addition, the BLA… Expand
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2006
2006
Chronic administration of antidepressants is required for their efficacy, suggesting the involvement of long-term modifications… Expand
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2004
2004
Studies suggest that behavioral, genomic, and endocrine functions mediated by central corticotropin-releasing factor (CRF… Expand
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2003
2003
4-(1,3-Dimethoxyprop-2-ylamine)-2,7-dimethyl-8-(2,4-dichlorophenyl)-pyrazolo[1,5-a]-1,3,5-triazine (DMP696) is a highly selective… Expand
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2003
2003
Mechanisms of nonpeptide ligand action at family B G protein-coupled receptors are largely unexplored. Here, we evaluated… Expand
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2002
2002
Abstract Rationale. CRF1 antagonists may be effective in the treatment of anxiety disorders while having fewer side effects… Expand
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2002
2002
We examined whether blockade of corticotropin-releasing factor (CRF) receptors by a non-peptide CRF antagonist (DMP696) would… Expand
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2000
2000
Structure-activity studies in the pyrazolo[1,5-a]-1,3,5-triazine series led to the discovery that compound 11i (DMP696) is a… Expand
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