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DMP 696

Known as: 4-(1,3-dimethoxy-2-propylamino)-2,7-dimethyl-8-(2,4-dichlorophenyl)(1,5-a)pyrazolo-1,3,5-triazine, DMP-696, DMP696 
 
National Institutes of Health

Papers overview

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2012
2012
Persistent dreadful memories and hyperarousal constitute prominent psychopathological features of posttraumatic stress disorder… Expand
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Highly Cited
2007
Highly Cited
2007
Chronic stress is widely regarded as a key risk factor for a variety of diseases. A large number of paradigms have been used to… Expand
Highly Cited
2007
Highly Cited
2007
The basolateral amygdala complex (BLA) and central amygdala nucleus (CeA) are involved in fear and anxiety. In addition, the BLA… Expand
Highly Cited
2006
Highly Cited
2006
Chronic administration of antidepressants is required for their efficacy, suggesting the involvement of long-term modifications… Expand
Review
2005
Review
2005
CRF(1) antagonists DMP696 and DMP904 were designed as drug development candidates for the treatment of anxiety and depression… Expand
2004
2004
Studies suggest that behavioral, genomic, and endocrine functions mediated by central corticotropin-releasing factor (CRF… Expand
Highly Cited
2003
Highly Cited
2003
4-(1,3-Dimethoxyprop-2-ylamine)-2,7-dimethyl-8-(2,4-dichlorophenyl)-pyrazolo[1,5-a]-1,3,5-triazine (DMP696) is a highly selective… Expand
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Highly Cited
2002
Highly Cited
2002
We examined whether blockade of corticotropin-releasing factor (CRF) receptors by a non-peptide CRF antagonist (DMP696) would… Expand
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2002
2002
Abstract Rationale. CRF1 antagonists may be effective in the treatment of anxiety disorders while having fewer side effects… Expand
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Highly Cited
2000
Highly Cited
2000
Structure-activity studies in the pyrazolo[1,5-a]-1,3,5-triazine series led to the discovery that compound 11i (DMP696) is a… Expand