DLST wt Allele

Known as: Alpha-Ketoglutarate Dehydrogenase Complex, E2 Component of Gene, DLTS, Dihydrolipoamide S-Succinyltransferase (E2 Component of 2-Oxo-Glutarate Complex) wt Allele 
Human DLST wild-type allele is located in the vicinity of 14q24.3 and is approximately 22 kb in length. This allele, which encodes… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2018
02040608019772018

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Currently, crizotinib is the only drug that has been approved for treatment of ALK-rearranged non-small-cell lung… (More)
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Highly Cited
2011
Highly Cited
2011
PURPOSE Preclinical models demonstrate synergistic antitumor activity with combination blockade of mTOR and IGF-1R signaling. We… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE To determine the recommended dose of everolimus, a mammalian target of rapamycin inhibitor, combined with paclitaxel and… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Everolimus is a selective mammalian target of rapamycin (mTOR) inhibitor with promising anticancer activity. In order to… (More)
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Highly Cited
2008
Highly Cited
2008
A Phase I trial (NCT00109109) of oral vorinostat 200, 250 or 300 mg twice daily for 5 days/week/4-week cycle or 200, 300, or 400… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE To assess the safety and tolerability, pharmacokinetics, and early evidence of antitumor activity of escalating doses of… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE The conversion rate of tegafur (a component of S-1) to fluorouracil (FU) differs in Asians and whites because of… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE To determine the maximum-tolerated dose (MTD), dose-limiting toxicity (DLT), and pharmacodynamics (PD) of the proteasome… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE To define the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of the novel protein kinase inhibitor, UCN-01… (More)
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Highly Cited
2000
Highly Cited
2000
The aim of this study was to examine the tolerability, antitumor activity, and biological effects of a new schedule of i.v… (More)
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