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DLST wt Allele

Known as: Alpha-Ketoglutarate Dehydrogenase Complex, E2 Component of Gene, DLTS, Dihydrolipoamide S-Succinyltransferase (E2 Component of 2-Oxo-Glutarate Complex) wt Allele 
Human DLST wild-type allele is located in the vicinity of 14q24.3 and is approximately 22 kb in length. This allele, which encodes… 
National Institutes of Health

Related topics

Related topics

4 relations
14q24.3Catabolic ProcessCell RespirationCitrate Cycle (TCA Cycle) Pathway

Papers overview

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Highly Cited
2015
Highly Cited
2015
Treatment with PF-04449913, an oral smoothened antagonist, in patients with myeloid malignancies: a phase 1 safety and pharmacokinetics study.
2011
2011
A phase I dose-escalation, safety and pharmacokinetic study of the 2-methoxyestradiol analog ENMD-1198 administered orally to patients with advanced cancer
SummaryBackground 2-methoxyestradiol (2ME2) is an estradiol-17β metabolite with antiproliferative and antiangiogenic activities… 
Highly Cited
2010
Highly Cited
2010
A phase I trial of PR-104, a nitrogen mustard prodrug activated by both hypoxia and aldo-keto reductase 1C3, in patients with solid tumors
PurposePR-104 is a “pre-prodrug” designed to be activated to a dinitrobenzamide nitrogen mustard cytotoxin by nitroreduction in… 
Highly Cited
2006
Highly Cited
2006
Phase I trial of UCN-01 in combination with topotecan in patients with advanced solid cancers: a Princess Margaret Hospital Phase II Consortium study.
BACKGROUND 7-Hydroxystaurosporine (UCN-01) inhibits serine-threonine kinases including the Ca2+ and phospholipid-dependent… 
Highly Cited
2006
Highly Cited
2006
Comparison of device performance and measured transport parameters in widely‐varying Cu(In,Ga) (Se,S) solar cells
We report the results of an extensive study employing numerous methods to characterize carrier transport within copper indium… 
Highly Cited
2005
Highly Cited
2005
Phase I Pharmacokinetic, Food Effect, and Pharmacogenetic Study of Oral Irinotecan Given as Semisolid Matrix Capsules in Patients with Solid Tumors
Purpose: To characterize the maximum-tolerated dose, recommended dose, dose-limiting toxicities (DLT), pharmacokinetic profile… 
Highly Cited
2001
Highly Cited
2001
Phase I trial of 72-hour continuous infusion UCN-01 in patients with refractory neoplasms.
PURPOSE To define the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of the novel protein kinase inhibitor, UCN-01… 
Highly Cited
1986
Highly Cited
1986
Identification of a defect in a semiconductor: EL2 in GaAs.
We present here a complete set of experimental results, obtained by electron paramagnetic resonance (EPR) and deep-level… 
Highly Cited
1982
Highly Cited
1982
Backgating in GaAs MESFET's
The phenomenon of backgating in GaAs depletion mode MESFET devices is investigated. The origin of this effect is electron… 
Highly Cited
1979
Highly Cited
1979
Phonon assisted tunnel emission of electrons from deep levels in GaAs
A theory is developed for the electric field emission of electrons from deep levels in GaAs taking into account quantum… 
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