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DKK2 gene

Known as: DKK2, DICKKOPF, XENOPUS, HOMOLOG OF, 2, dickkopf WNT signaling pathway inhibitor 2 
This gene plays a role in the regulation of Wnt signaling.
National Institutes of Health

Papers overview

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2017
2017
Purpose To examine the role of miR-106b-5p in regulating the cancer stem-cell-like phenotype in clear cell renal cell carcinomas… 
Highly Cited
2016
Highly Cited
2016
Background: Chemoresistance is a main obstacle to effective esophageal cancer (EC) therapy. We hypothesize that altered… 
2015
2015
Bone is established as the preferred site of breast cancer metastasis. However, the precise mechanisms responsible for this… 
Highly Cited
2013
Highly Cited
2013
MicroRNA-21 (miR-21) is overexpressed in a wide variety of cancers and has been related to cellular proliferation, apoptosis, and… 
Highly Cited
2011
Highly Cited
2011
The Wnt signaling pathway is crucial for osteogenesis and regulates terminal osteoblast differentiation. Although osteoarthritic… 
Highly Cited
2010
Highly Cited
2010
Wnt/LRP5 signaling is a central regulatory component of bone formative and resorptive activities, and the pathway inhibitor DKK1… 
Highly Cited
2009
Highly Cited
2009
Purpose: Wnt/β-catenin signaling is involved in renal cancer. DKK2, a Wnt antagonist, is silenced in some cancers, although its… 
Highly Cited
2008
Highly Cited
2008
Using a moderate‐sized cohort selected with extreme BMD (n = 344; absolute value BMD, 1.5–4.0), significant association of…