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DKK2 gene

Known as: DKK2, DICKKOPF, XENOPUS, HOMOLOG OF, 2, dickkopf WNT signaling pathway inhibitor 2 
This gene plays a role in the regulation of Wnt signaling.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
  • Yan Wang, Yue Zhao, +13 authors C. Bruns
  • Annals of surgery
  • 2016
  • Corpus ID: 39518700
Background: Chemoresistance is a main obstacle to effective esophageal cancer (EC) therapy. We hypothesize that altered… Expand
2015
2015
Bone is established as the preferred site of breast cancer metastasis. However, the precise mechanisms responsible for this… Expand
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Highly Cited
2014
Highly Cited
2014
Human adipose-derived stem cells (hASCs) have become a highly attractive source of seed cells in bone regenerative. It has become… Expand
Highly Cited
2013
Highly Cited
2013
MicroRNA-21 (miR-21) is overexpressed in a wide variety of cancers and has been related to cellular proliferation, apoptosis, and… Expand
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2012
2012
Wnt/β-Catenin signaling dysregulation is involved in tumorigenesis. Furthermore, epigenetic modification of the Dickkopf (DKK… Expand
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Highly Cited
2010
Highly Cited
2010
Wnt/LRP5 signaling is a central regulatory component of bone formative and resorptive activities, and the pathway inhibitor DKK1… Expand
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Highly Cited
2009
Highly Cited
2009
Purpose: Wnt/β-catenin signaling is involved in renal cancer. DKK2, a Wnt antagonist, is silenced in some cancers, although its… Expand
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Highly Cited
2008
Highly Cited
2008
Using a moderate‐sized cohort selected with extreme BMD (n = 344; absolute value BMD, 1.5–4.0), significant association of… Expand
Highly Cited
2008
Highly Cited
2008
Local control of cell signaling activity and integration of inputs from multiple signaling pathways are central for normal… Expand
Highly Cited
2007
Highly Cited
2007
Activation of Wnt signaling has been implicated in tumorigenesis, and epigenetic silencing of Wnt antagonist genes has been… Expand