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DIO2 gene

Known as: DIO2, D2, deiodinase-2 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Social cues regulate reciprocal switching of hypothalamic Dio2/Dio3 and the transition into final follicle maturation in European starlings (Sturnus vulgaris).
With final maturation of ovarian follicles, birds are committed to a major energetic investment: egg laying. Follicles develop in… 
2014
2014
Hydrodynamic delivery of FGF21 gene alleviates obesity and fatty liver in mice fed a high-fat diet.
2014
2014
RNA-seq analysis of the rat placentation site reveals maternal obesity-associated changes in placental and offspring thyroid hormone signaling.
Review
2014
Review
2014
Regulatory SNPs and transcriptional factor binding sites in ADRBK1, AKT3, ATF3, DIO2, TBXA2R and VEGFA
Abstract Regulatory single nucleotide polymorphisms (rSNPs) which change the transcriptional factor binding sites (TFBS) for… 
2012
2012
Association analyses of variants in the DIO2 gene with early-onset type 2 diabetes mellitus in Pima Indians.
BACKGROUND The type 2 deiodinase gene (DIO2) encodes a deiodinase that converts the thyroid prohormone, thyroxine, to the… 
2012
2012
Thyroid hormone-dependent development in Xenopus laevis: a sensitive screen of thyroid hormone signaling disruption by municipal wastewater treatment plant effluent.
Highly Cited
2008
Highly Cited
2008
Identification of Uterine Leiomyoma Genes Developmentally Reprogrammed by Neonatal Exposure to Diethylstilbestrol
Environmental exposures during development can alter susceptibility later in life to adult diseases including uterine leiomyoma… 
2007
2007
The type 2 deiodinase (DIO2) A/G polymorphism is not associated with glycemic traits: the Framingham Heart Study.
BACKGROUND Type 2 deiodinase plays a critical role in thyroid hormone homeostasis. A single nucleotide polymorphism in DIO2 gene… 
2007
2007
The role of repressor proteins in the adrenergic induction of type II iodothyronine deiodinase in rat pinealocytes.
In this study, we investigated the transcriptional regulation of the adrenergic induction of type II iodothyronine deiodinase… 
2003
2003
The different cardiac expression of the type 2 iodothyronine deiodinase gene between human and rat is related to the differential response of the Dio2 genes to Nkx-2.5 and GATA-4 transcription…
By producing T3 from T4, type 2 iodothyronine deiodinase (D2) catalyzes the first step in the cascade underlying the effect… 
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