Skip to search formSkip to main contentSkip to account menu

DGKE gene

Known as: diacylglycerol kinase epsilon, DGKE, DIACYLGLYCEROL KINASE, EPSILON, 64-KD 
National Institutes of Health

Related topics

Related topics

3 relations
DGKA geneDGKB geneDGKZ gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Atypical hemolytic uremic syndrome with diacylglycerol kinase epsilon (DGKE) gene mutation
Atypical hemolytic uremic syndrome (aHUS), an important cause of acute kidney injury requiring dialysis in children, is caused by… 
2019
2019
Diacylglycerol kinase epsilon nephropathy: late diagnosis and therapeutic implications
Abstract A 17-year-old male presented thrombotic microangiopathy (TMA) at 6 months of age with arterial hypertension, anemia… 
Highly Cited
2018
Highly Cited
2018
Statistical Validation of Rare Complement Variants Provides Insights into the Molecular Basis of Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy
Atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G) are associated with dysregulation and overactivation of the… 
2017
2017
The Phenotypic Spectrum of Nephropathies Associated with Mutations in Diacylglycerol Kinase ε.
The recent discovery of mutations in the gene encoding diacylglycerol kinase ε (DGKE) identified a novel pathophysiologic… 
Review
2016
Review
2016
DGK-θ: Structure, Enzymology, and Physiological Roles
Diacylglycerol kinases (DGKs) are a family of enzymes that catalyze the ATP-dependent phosphorylation of diacylglycerol (DAG) to… 
Highly Cited
2015
Highly Cited
2015
Characterization of a New DGKE Intronic Mutation in Genetically Unsolved Cases of Familial Atypical Hemolytic Uremic Syndrome.
BACKGROUND AND OBJECTIVES Genetic and acquired abnormalities causing dysregulation of the complement alternative pathway… 
Highly Cited
2013
Highly Cited
2013
Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome
Pathologic thrombosis is a major cause of mortality. Hemolytic-uremic syndrome (HUS) features episodes of small-vessel thrombosis… 
Highly Cited
2013
Highly Cited
2013
DGKE variants cause a glomerular microangiopathy that mimics membranoproliferative GN.
Renal microangiopathies and membranoproliferative GN (MPGN) can manifest similar clinical presentations and histology, suggesting… 
2007
2007
Role of the hydrophobic segment of diacylglycerol kinase epsilon.
Diacylglycerol kinase epsilon (DGKepsilon) is unique among mammalian DGK isoforms in having a segment of hydrophobic amino acids… 
2007
2007
Membrane interactions of the hydrophobic segment of diacylglycerol kinase epsilon.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)