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DGCR8 gene

Known as: Gy1, DGCRK6, DGCR8 Microprocessor Complex Subunit Gene 
This gene plays a role in microRNA processing.
National Institutes of Health

Related topics

Related topics

7 relations
DGCR geneDiGeorge SyndromeLigand BindingMicroRNA Synthesis

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DGCR8 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
A central role for the primary microRNA stem in guiding the position and efficiency of Drosha processing of a viral pri-miRNA
This paper addresses the mechanism of recognition and cleavage of primary microRNAs (pri-miRNAs) by the Microprocessor (DGCR8… 
2014
2014
Drosha-independent DGCR8/Pasha pathway regulates neuronal morphogenesis
Significance Understanding the neuronal functions of diverse RNA pathways will lead to treatments of human neurological diseases… 
2012
2012
Rare Drosha splice variants are deficient in microRNA processing but do not affect general microRNA expression in cancer cells.
Drosha is a key enzyme in microRNA biogenesis, generating the precursor miRNA (pre-miRNA) by excising the stem-loop embedded in… 
2011
2011
Downregulation of Dicer, a component of the microRNA machinery, in bladder cancer.
Dysregulation of microRNA metabolism has been observed in a variety of human cancers. In this study, we evaluated the… 
2011
2011
A Drosophila genetic screen yields allelic series of core microRNA biogenesis factors and reveals post-developmental roles for microRNAs.
Canonical animal microRNAs (miRNAs) are ∼22-nt regulatory RNAs generated by stepwise cleavage of primary hairpin transcripts by… 
2010
2010
Solution structure of the Drosha double-stranded RNA-binding domain
BackgroundDrosha is a nuclear RNase III enzyme that initiates processing of regulatory microRNA. Together with partner protein… 
Highly Cited
2008
Highly Cited
2008
A Drosophila pasha Mutant Distinguishes the Canonical MicroRNA and Mirtron Pathways
ABSTRACT Canonical primary microRNA (miRNA) transcripts and mirtrons are proposed to transit distinct nuclear pathways en route… 
1997
1997
Levels of HCH Residues in Human Milk Samples from Delhi, India
Levels of HCH Residues in Human Milk Samples from Delhi, India B. D. Banerjee, S. S. A. Zaidi, S. T. Pasha, D. S. Rawak, 3 B. C… 
Highly Cited
1989
Highly Cited
1989
Inheritance and Organization of Glycinin Genes in Soybean.
Five genes (Gy1, through Gy5) encode most of the subunits that are assembled into glycinin, a predominant seed storage protein… 
Highly Cited
1979
Highly Cited
1979
Incomplete transformation of rat cells by a small fragment of adenovirus 12 DNA.
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