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DEFB4A gene

Known as: DEFENSIN, BETA, 2, FORMERLY, DEFB-2, DEFENSIN, BETA, 4, FORMERLY 
National Institutes of Health

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2 relations
DEFB104A geneDEFB4A protein, human

Papers overview

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Highly Cited
2007
Highly Cited
2007
β‐Defensins chemoattract macrophages and mast cells but not lymphocytes and dendritic cells: CCR6 is not involved
β‐Defensins are natural peptide antibiotics whose immunomodulatory functions are poorly understood. In the present study… 
Highly Cited
2004
Highly Cited
2004
Human β-Defensins 2 and 3 Demonstrate Strain-Selective Activity against Oral Microorganisms
ABSTRACT Human β-defensins 2 and 3 (HBD-2 and HBD-3) are inducible peptides present at sites of infection in the oral cavity. A… 
Highly Cited
2004
Highly Cited
2004
Human Rhinovirus Infection Induces Airway Epithelial Cell Production of Human β-Defensin 2 Both In Vitro and In Vivo1
We hypothesized that airway epithelial cells, the primary site of human rhinovirus (HRV) infection, provide a link between the… 
Highly Cited
2003
Highly Cited
2003
Defensin expression by the cornea: multiple signalling pathways mediate IL-1beta stimulation of hBD-2 expression by human corneal epithelial cells.
PURPOSE To investigate the expression of human beta-defensins (hBDs) by human corneal epithelium and determine the effects of… 
Highly Cited
2002
Highly Cited
2002
The Solution Structures of the Human β-Defensins Lead to a Better Understanding of the Potent Bactericidal Activity of HBD3 against Staphylococcus aureus *
The three human β-defensins, HBD1–3, are 33–47-residue, cationic antimicrobial proteins expressed by epithelial cells. All three… 
Highly Cited
2002
Highly Cited
2002
The novel human beta-defensin-3 is widely expressed in oral tissues.
The purpose of this study was to investigate the expression of human beta-defensins (hBD), especially of the recently discovered… 
Highly Cited
2001
Highly Cited
2001
Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells.
Antimicrobial peptides, human beta-defensins (hBD-1/-2), and LL-37 (a peptide of human cathelicidin CAP18) are predominately… 
Highly Cited
2000
Highly Cited
2000
Inducible Expression of Human β-Defensin 2 byFusobacterium nucleatum in Oral Epithelial Cells: Multiple Signaling Pathways and Role of Commensal Bacteria in Innate Immunity and the Epithelial Barrier
ABSTRACT Human gingival epithelial cells (HGE) express two antimicrobial peptides of the β-defensin family, human β-defensin 1… 
Highly Cited
2000
Highly Cited
2000
Transcriptional Regulation of β-Defensin Gene Expression in Tracheal Epithelial Cells
ABSTRACT Innate immunity provides an ever-present or rapidly inducible initial defense against microbial infection. Among the… 
Highly Cited
1999
Highly Cited
1999
Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.
The intestinal epithelium forms a physical barrier to limit access of enteric microbes to the host and contributes to innate host… 
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