DDX4 gene

Known as: VASA, DDX4, DEAD-box helicase 4 
 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila.
Model organisms such as the fruit fly Drosophila melanogaster can help to elucidate the molecular basis of complex diseases such… (More)
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Highly Cited
2007
Highly Cited
2007
Gene silencing mechanisms mediated by Aubergine piRNA complexes in Drosophila male gonad.
Genetic studies have shown that Aubergine (Aub), one of the Piwi subfamily of Argonautes in Drosophila, is essential for germ… (More)
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Highly Cited
2006
Highly Cited
2006
The Role of PIWI and the miRNA Machinery in Drosophila Germline Determination
BACKGROUND The germ plasm has long been demonstrated to be necessary and sufficient for germline determination, with… (More)
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Highly Cited
2003
Highly Cited
2003
Maelstrom, a Drosophila spindle-class gene, encodes a protein that colocalizes with Vasa and RDE1/AGO1 homolog, Aubergine, in nuage.
A hallmark of germline cells across the animal kingdom is the presence of perinuclear, electron-dense granules called nuage. In… (More)
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Highly Cited
2000
Highly Cited
2000
The human VASA gene is specifically expressed in the germ cell lineage.
To understand the origins and function of the human germ cell lineage and to identify germ cell-specific markers we have isolated… (More)
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Highly Cited
1998
Highly Cited
1998
Regulation of zygotic gene expression in Drosophila primordial germ cells
Activation of the zygotic genome is a prerequisite for the transition from maternal to zygotic control of development. The onset… (More)
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Highly Cited
1998
Highly Cited
1998
Enhanced coronary vasa vasorum neovascularization in experimental hypercholesterolemia.
Coronary arteries contain a network of vasa vasorum in the adventitia. The three-dimensional anatomy of the vasa vasorum in early… (More)
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Highly Cited
1992
Highly Cited
1992
Induction of germ cell formation by oskar
The oskar gene directs germ plasm assembly and controls the number of germ cell precursors formed at the posterior pole of the… (More)
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Highly Cited
1991
Highly Cited
1991
The maternal gene nanos has a central role in posterior pattern formation of the Drosophila embryo.
A group of maternal genes, the posterior group, is required for the development of the abdominal region in the Drosophila embryo… (More)
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Highly Cited
1988
Highly Cited
1988
The product of the Drosophila gene vasa is very similar to eukaryotic initiation factor-4A
The vasa gene product of Drosophila melanogaster is required only in the female germ line. Progeny of females homozygous for vasa… (More)
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