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DCTPP1 gene

Known as: XTP3-transactivated protein A, dCTP pyrophosphatase 1, XTP3TPA 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Abstract 1267: Unusual mechanism of resistance to the novel cytidine analog fluorocyclopentenylcytosine (RX-3117)
RX-3117 is a novel cytidine analog showing encouraging results in ongoing Phase 2a studies with gemcitabine-resistant pancreatic… 
2017
2017
Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors.
The dCTP pyrophosphatase 1 (dCTPase) is a nucleotide pool "housekeeping" enzyme responsible for the catabolism of canonical and… 
2017
2017
Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 2: Pyridone- and pyrimidinone-derived systems.
2017
2017
The nucleotidohydrolases DCTPP 1 and dUTPase are involved in the cellular response to the DNA-demethylating drug decitabine
Decitabine (5-aza-2’-deoxycytidine, aza-dCyd) is a potent DNA-demethylating and genotoxic drug used clinically for the treatment… 
2016
2016
Discovery of the first potent and selective inhibitors of the human dCTP pyrophosphatase 1 (dCTPase)
2014
2014
Caracterización de la NTP pirofosfatasa humana DCTPP1 y su papel en la homeostasis intracelular de nucleótidos
El mantenimiento de la integridad de la informacion genetica contenida en el DNA es uno de los mayores retos con los que se… 
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