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Cytochrome p450 CYP2J2 enzyme

Known as: CYP2J2, cytochrome P-450 CYP2J2 
National Institutes of Health

Related topics

Related topics

2 relations
CYP2J2 gene

Broader (1)

arachidonate epoxygenase

Papers overview

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Highly Cited
2015
Highly Cited
2015
Epoxyeicosatrienoic Acids Regulate Macrophage Polarization and Prevent LPS‐Induced Cardiac Dysfunction
Macrophages, owning tremendous phenotypic plasticity and diverse functions, were becoming the target cells in various… 
Highly Cited
2012
Highly Cited
2012
Let-7b Inhibits Human Cancer Phenotype by Targeting Cytochrome P450 Epoxygenase 2J2
Background MicroRNAs (miRNAs) are small, noncoding RNA molecules of 20 to 22 nucleotides that regulate gene expression by binding… 
Highly Cited
2012
Highly Cited
2012
Delivery of AAV2-CYP2J2 protects remnant kidney in the 5/6-nephrectomized rat via inhibition of apoptosis and fibrosis.
The cytochrome P450 epoxygenase, CYP2J2, converts arachidonic acid to four regioisomeric epoxyeicosatrienoic acids (EETs), which… 
Highly Cited
2009
Highly Cited
2009
Selective Inhibitors of CYP2J2 Related to Terfenadine Exhibit Strong Activity against Human Cancers in Vitro and in Vivo
The cytochrome P450 epoxygenase, CYP2J2, converts arachidonic acid to four regioisomeric epoxyeicosatrienoic acids (EETs). We… 
Highly Cited
2007
Highly Cited
2007
Unusual regioselectivity and active site topology of human cytochrome P450 2J2.
The oxidation of six derivatives of terfenadone by recombinant human CYP2J2 (CYP = cytochrome P450) was studied by high… 
Highly Cited
2006
Highly Cited
2006
Characterization of rat and human CYP2J enzymes as Vitamin D 25-hydroxylases
Highly Cited
2004
Highly Cited
2004
Enhancement of Cardiac L-Type Ca2+ Currents in Transgenic Mice with Cardiac-Specific Overexpression of CYP2J2
CYP2J2 is abundant in cardiomyocytes and is involved in the metabolism of arachidonic acid (AA) to epoxyeicosatrienoic acids… 
Highly Cited
1997
Highly Cited
1997
CYP2J subfamily cytochrome P450s in the gastrointestinal tract: expression, localization, and potential functional significance.
Our laboratory recently described a new human cytochrome P450 arachidonic acid epoxygenase (CYP2J2) and the corresponding rat… 
Highly Cited
1997
Highly Cited
1997
Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas.
Our laboratory recently described a new human cytochrome P450 arachidonic acid epoxygenase (CYP2J2) and the corresponding rat… 
Highly Cited
1996
Highly Cited
1996
CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance.
Cytochrome P450 (P450) monooxygenases catalyze the epoxidation of arachidonic acid to form epoxyeicosatrienoic acids, which… 
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