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Cystine/Glutamate Transporter Protein

Known as: System Xc(-) Transporter-Related Protein, Amino Acid Transport System xc-, XCT 
Cystine/glutamate transporter protein (501aa, ~55 kDa) is encoded by the human SLC7A11 gene. This protein is involved in the exchange of anionic… Expand
National Institutes of Health

Papers overview

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2017
2017
Cancer cells with specific genetic alterations may be highly dependent on certain nutrients for survival, which can inform… Expand
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2016
2016
The xCT light chain of the cystine/glutamate transporter (system XC-) is of importance for the survival of triple-negative breast… Expand
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2015
2015
Glioblastomas (GBMs) are aggressive brain tumors that always recur after radiotherapy. Cystine, mainly provided by the system Xc… Expand
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2014
2014
Liver-specific Nrf1 (NF-E2-p45-related factor 1) knockout mice develop nonalcoholic steatohepatitis. To identify postnatal… Expand
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2007
2007
Reactive oxygen species (ROS) produced by neutrophils are essential in the host defense against infections but may be harmful to… Expand
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2007
2007
BackgroundCystine/glutamate transporter, system xc-, contributes to the maintenance of intracellular glutathione levels and the… Expand
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Highly Cited
2005
Highly Cited
2005
Cystine/glutamate transporter, designated as system x(-)(c), mediates cystine entry in exchange for intracellular glutamate in… Expand
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Highly Cited
2004
Highly Cited
2004
Recent studies have demonstrated that depletion of amino acids results in the induction of several genes and that a genomic cis… Expand
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Highly Cited
2001
Highly Cited
2001
PURPOSE The purpose of this investigation was to provide evidence for the expression of the cystine/glutamate transporter (x(c… Expand
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Highly Cited
2001
Highly Cited
2001
A human cDNA for amino acid transport system x(C)(-) was isolated from diethyl maleate-treated human glioma U87 cells. U87 cells… Expand
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