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Cyclacillin

Known as: Ciclacilline, Ciclacilina, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-(((1-aminocyclohexyl)carbonyl)amino)-3,3-dimethyl-7-oxo-,(2S-(2alpha,5alpha,6beta))- 
A semi-synthetic beta-lactam aminocyclohexylpenicillin antibiotic. Cyclacillin is bactericidal and binds to specific penicillin-binding proteins… 
National Institutes of Health

Related topics

Related topics

19 relations

Broader (1)

Anti-Bacterial Agents
Cyclacillin:Susc:Pt:Isolate:OrdQn:Gradient stripCyclacillin:Susc:Pt:Isolate:OrdQn:MICDrug AllergyHaemophilus Infections

Narrower (3)

UltracillinVastcillinWy-4508

Papers overview

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Highly Cited
2006
Highly Cited
2006
Transport Characteristics of a Novel Peptide Transporter 1 Substrate, Antihypotensive Drug Midodrine, and Its Amino Acid Derivatives
Midodrine is an oral drug for orthostatic hypotension. This drug is almost completely absorbed after oral administration and… 
1995
1995
The Influence of Uptake from the Gastrointestinal Tract and First‐pass Effect on Oral Bioavailability of (Z)‐alkyloxyimino Penicillins
We have investigated the contribution of uptake from the gastrointestinal tract and first‐pass effect to the poor oral… 
1986
1986
Comparison of cyclacillin and amoxicillin for therapy for acute maxillary sinusitis
Cyclacillin, a new aminosalicylic semisynthetic penicillin, was compared with amoxicillin for the therapy of acute bacterial… 
1985
1985
Transport of cefadroxil, an aminocephalosporin antibiotic, across the small intestinal brush border membrane.
1980
1980
[Studies on the distributions of antibiotics in the oral tissues: Experimental staphylococcal infection in rats, and effect of serratiopeptidase on the distributions of antibiotics (author's transl…
1) A focal infection was prepared by inoculation of staphylococci into rat gingiva. Then, concentrations in oral tissues (gingiva… 
1980
1980
Effect of cyclacillin and ampicillin on the gut flora of mice.
The oral administration of cyclacillin, a semisynthetic aminoalicyclic penicillin, results in the elimination of the lactobacilli… 
1979
1979
Double-Blind Clinical Trials of Oral Cyclacillin and Ampicillin
A double-blind study was performed to compare the clinical response and the incidence of side effects in 2,581 patients… 
1974
1974
The effect of antimicrobial agents on human faecal flora: studies with cephalexin, cyclacillin and clindamycin.
1973
1973
Serum and Urinary Concentrations of Cyclacillin in Humans
Cyclacillin is a semisynthetic penicillin produced from the penicillin nucleus (6-aminopenicillanic acid) by acylation with 1… 
Highly Cited
1969
Highly Cited
1969
The amino acid nature of ampicillin and related penicillins.
The amphoteric penicillins, ampicillin and Wy-4508 (cyclacillin), possess properties similar to the alicyclacillinphatic amino… 
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