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Cyclacillin

Known as: Ciclacilline, Ciclacilina, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-(((1-aminocyclohexyl)carbonyl)amino)-3,3-dimethyl-7-oxo-,(2S-(2alpha,5alpha,6beta))- 
A semi-synthetic beta-lactam aminocyclohexylpenicillin antibiotic. Cyclacillin is bactericidal and binds to specific penicillin-binding proteins… Expand
National Institutes of Health

Papers overview

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2006
2006
Midodrine is an oral drug for orthostatic hypotension. This drug is almost completely absorbed after oral administration and… Expand
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2005
2005
The activity of the renal peptide transporters PEPT2 and PEPT1 determines-among other factors such as metabolic stability in… Expand
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Highly Cited
2004
Highly Cited
2004
AbstractPurpose. This study on the intestinal transport of β-lactam antibiotics was undertaken to investigate the correlation… Expand
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1997
1997
PEPT1 and PEPT2 are H(+)-coupled peptide transporters expressed preferentially in the intestine and kidney, respectively, which… Expand
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Highly Cited
1995
Highly Cited
1995
This study was initiated to determine if there are differences in the recognition of beta -lactam antibiotics as substrates… Expand
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1986
1986
A predictable 6- to 7-day course of a fatal Leptospira interrogans serovar bataviae infection in experimentally infected mature… Expand
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1985
1985
The inhibition effect of several beta-lactam antibiotics on the uptake of [14C]benzylpenicillin (PCG) into isolated rat… Expand
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1985
1985
Abstract “Single-Dose Therapy for Cystitis in Women: A Comparison of Trimethoprim-Sulfamethoxazole, Amoxicillin, and Cyclacillin… Expand
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1979
1979
A double-blind study was performed to compare the clinical response and the incidence of side effects in 2,581 patients… Expand
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1973
1973
SummaryIn 50 adults with bacterial sinusitis, cyclacillin (1500 mg. per day for 7 days) proved significantly more effective than… Expand
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