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Cyclacillin

Known as: Ciclacilline, Ciclacilina, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-(((1-aminocyclohexyl)carbonyl)amino)-3,3-dimethyl-7-oxo-,(2S-(2alpha,5alpha,6beta))- 
A semi-synthetic beta-lactam aminocyclohexylpenicillin antibiotic. Cyclacillin is bactericidal and binds to specific penicillin-binding proteins… Expand
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
AbstractPurpose. This study on the intestinal transport of β-lactam antibiotics was undertaken to investigate the correlation… Expand
Highly Cited
1997
Highly Cited
1997
PEPT1 and PEPT2 are H+-coupled peptide transporters expressed preferentially in the intestine and kidney, respectively, which… Expand
Highly Cited
1995
Highly Cited
1995
This study was initiated to determine if there are differences in the recognition of β-lactam antibiotics as substrates between… Expand
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1985
1985
High-performance liquid chromatographic methods have been developed for the determination of ampicillin (ABPC), amoxicillin (AMPC… Expand
1985
1985
We evaluated single-dose regimens of trimethoprim-sulfamethoxazole, amoxicillin, and cyclacillin as treatment for acute cystitis… Expand
1979
1979
A double-blind study was performed to compare the clinical response and the incidence of side effects in 2,581 patients… Expand
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Highly Cited
1978
Highly Cited
1978
The degradation rate, solubility, and dissolution rate of amino penicillins, amoxicillin, ampicillin, epicillin, and cyclacillin… Expand
1976
1976
Summary Incubation of Escherichia coli with sublethal concentrations of the semisynthetic penicillins cyclacillin and ampicil-lin… Expand
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1973
1973
SummaryIn 50 adults with bacterial sinusitis, cyclacillin (1500 mg. per day for 7 days) proved significantly more effective than… Expand
1973
1973
  • C. Hertz
  • Antimicrobial Agents and Chemotherapy
  • 1973
  • Corpus ID: 30940670
Cyclacillin is a semisynthetic penicillin produced from the penicillin nucleus (6-aminopenicillanic acid) by acylation with 1… Expand
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