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Cyclacillin
Known as:
Ciclacilline
, Ciclacilina
, 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-(((1-aminocyclohexyl)carbonyl)amino)-3,3-dimethyl-7-oxo-,(2S-(2alpha,5alpha,6beta))-
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A semi-synthetic beta-lactam aminocyclohexylpenicillin antibiotic. Cyclacillin is bactericidal and binds to specific penicillin-binding proteins…
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National Institutes of Health
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Related topics
Related topics
19 relations
Broader (1)
Anti-Bacterial Agents
Cyclacillin:Susc:Pt:Isolate:OrdQn:Gradient strip
Cyclacillin:Susc:Pt:Isolate:OrdQn:MIC
Drug Allergy
Haemophilus Infections
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Narrower (3)
Ultracillin
Vastcillin
Wy-4508
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1981
1981
High performance liquid chromatographic determination and pharmacokinetic investigation of amino-penicillins and their metabolites in man.
T. Uno
,
M. Masada
,
K. Yamaoka
,
T. Nakagawa
Chemical and pharmaceutical bulletin
1981
Corpus ID: 31814715
The metabolism and pharmacokinetics of amino-penicillins such as ampicillin (AB-PC), hetacillin (IPAB-PC), talampicillin (TA-PC…
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1980
1980
[Studies on the distributions of antibiotics in the oral tissues: Experimental staphylococcal infection in rats, and effect of serratiopeptidase on the distributions of antibiotics (author's transl…
H. Aratani
,
H. Tateishi
,
S. Negita
The Japanese Journal of Antibiotics
1980
Corpus ID: 39872329
1) A focal infection was prepared by inoculation of staphylococci into rat gingiva. Then, concentrations in oral tissues (gingiva…
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1979
1979
Double-Blind Clinical Trials of Oral Cyclacillin and Ampicillin
J. A. Gold
,
C. Hegarty
,
M. Deitch
,
B. Walker
Antimicrobial Agents and Chemotherapy
1979
Corpus ID: 39135745
A double-blind study was performed to compare the clinical response and the incidence of side effects in 2,581 patients…
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1977
1977
Cyclacillin-induced potentiation of Escherichia coli immunogenicity in vivo and in vitro.
H. Friedman
,
G. Warren
Chemotherapy
1977
Corpus ID: 19713837
The efficacy of cyclacillin as an antimicrobial agent against Escherichia coli was assessed in vivo in mice infected with low…
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Review
1976
Review
1976
Cyclacillin: microbiological and pharmacological properties and use in chemotherapy of infection - a critical appraisal.
G. Warren
Chemotherapy
1976
Corpus ID: 46849478
The pharmacological and microbiological properties of cyclacillin were discussed and its usefulness in the management of a…
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1976
1976
Comparative studies of the activity of ciclacillin and dicloxacillin.
H. Mückter
,
H. Sous
,
G. Poszich
,
Peter Arend
Chemotherapy
1976
Corpus ID: 3298395
The penicillins ciclacillin and dicloxacillin demonstrate marked similarities in biological activity but, as far as can be…
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1974
1974
Cyclacillin: a clinical and in vitro profile.
A. Gonzaga
,
M. Antonio-Velmonte
,
T. Tupasi
Journal of Infectious Diseases
1974
Corpus ID: 36291375
The levels of orally administered cyclacillin and ampicillin were determined in serum and urine of 11 healthy male volunteers…
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1973
1973
Serum and Urinary Concentrations of Cyclacillin in Humans
C. Hertz
Antimicrobial Agents and Chemotherapy
1973
Corpus ID: 30940670
Cyclacillin is a semisynthetic penicillin produced from the penicillin nucleus (6-aminopenicillanic acid) by acylation with 1…
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1972
1972
Measurement of beta-lactamase activity and rate of inactivation of penicillins by a pH-stat alkalimetric titration method.
J. Hou
,
J. W. Poole
Journal of Pharmacy and Science
1972
Corpus ID: 29307857
The pH-stat alkalimetric titration method was shown to be applicable and superior to other chemical methods in the investigation…
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1970
1970
Cyclacillin, a semisynthetic aminoalicyclic penicillin. I. Antibacterial activity in vitro and in vivo compared with ampicillin and cephalexin.
J. A. Yurchenco
,
M. W. Hopper
,
T. Vince
,
G. Warren
Chemotherapy
1970
Corpus ID: 3238635
Cyclacillin was compared with cephalex-in and ampicillin for activity against various patho- gens in vitro and the corresponding…
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