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Cullin-4B

Known as: CUL-4B 
Cullin-4B (895 aa, ~102 kDa) is encoded by the human CUL4B gene. This protein plays a role in both ubiquitination and protein-protein interactions.
National Institutes of Health

Related topics

Related topics

8 relations
CUL4B geneCullin Family ProteinGenes, RegulatorHomo sapiens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Cullin-4B E3 ubiquitin ligase mediates Apaf-1 ubiquitination to regulate caspase-9 activity
Apoptotic protease-activating factor 1 (Apaf-1) is a component of apoptosome, which regulates caspase-9 activity. In addition to… 
2018
2018
MiR-431 inhibits colorectal cancer cell invasion via repressing CUL4B.
OBJECTIVE To detect the expression of microRNA-431 (miR-431) in epithelial-mesenchymal transition (EMT) in colorectal carcinoma… 
2015
2015
Variants in CUL4B are Associated with Cerebral Malformations
Variants in cullin 4B (CUL4B) are a known cause of syndromic X‐linked intellectual disability. Here, we describe an additional 25… 
2014
2014
Cullin4A and Cullin4B Are Interchangeable for HIV Vpr and Vpx Action through the CRL4 Ubiquitin Ligase Complex
ABSTRACT Human immunodeficiency virus (HIV) seizes control of cellular cullin-RING E3 ubiquitin ligases (CRLs) to promote viral… 
2014
2014
CRL 4 Ubiquitin Ligase Complex for HIV Vpr and Vpx Action through the Cullin 4 A and Cullin 4 B Are Interchangeable
Human immunodeficiency virus (HIV) seizes control of cellular cullin-RING E3 ubiquitin ligases (CRLs) to promote viral… 
2013
2013
Glycoproteomic analysis of bronchoalveolar lavage (BAL) fluid identifies tumor-associated glycoproteins from lung adenocarcinoma.
Cytological examination of cells from bronchoalveolar lavage (BAL) is commonly used for the diagnosis of lung cancer. Proteins… 
2012
2012
Cul4B regulates neural progenitor cell growth
BackgroundCullin ubiquitin ligases are activated via the covalent modification of Cullins by the small ubiquitin-like protein… 
2012
2012
Insights into a heteromeric protein arginine N-methyltransferase complex
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Highly Cited
1999
Highly Cited
1999
Covalent modification of all members of human cullin family proteins by NEDD8
Recently we found that NEDD8, a ubiquitin-like protein, was linked covalently to human cullin-4A (abbreviated Cul-4A) by a new… 
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