Cosyntropin

Known as: corticotropin-(1-24) tetracosapeptide, beta(1-24)-corticotrophin, β1-24-corticotrophin 
A synthetically-derived subunit of the endogenous peptide pituitary hormone adrenocorticotropic hormone (ACTH). Consisting of the first 24 amino… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1963-2018
0204019632018

Papers overview

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Review
2015
Review
2015
BACKGROUND Glucocorticoids as diagnostic or therapeutic agents have been reported to carry an increased risk of catecholaminergic… (More)
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Highly Cited
2006
Highly Cited
2006
CONTEXT Severe systemic infection leads to hypercortisolism. Reduced cortisol binding proteins may accentuate the free cortisol… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Because more than 90 percent of circulating cortisol in human serum is protein-bound, changes in the binding proteins… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Infantile spasms, which comprise a severe infantile seizure disorder, have a high morbidity and are difficult to treat… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE To evaluate the outcome of children with cryptogenic infantile spasms treated with high-dose synthetic… (More)
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Highly Cited
2000
Highly Cited
2000
CONTEXT The hypothalamic-pituitary-adrenal axis is a major determinant of the host response to stress. The relationship between… (More)
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Highly Cited
1999
Highly Cited
1999
There is still uncertainty about what is the most appropriate test for assessment of the integrity of the hypothalamo-pituitary… (More)
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Highly Cited
1998
Highly Cited
1998
Tetracosactin [corticotropin-(1-24)] is used for clinical testing of adrenocortical responsiveness. The usual dose [high dose… (More)
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Highly Cited
1996
Highly Cited
1996
OBJECTIVE The insulin tolerance test (ITT) has long been used to assess the hypothalamic-pituitary-adrenal axis, but may be… (More)
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Highly Cited
1985
Highly Cited
1985
The complete primary structure of the 3.1S leucine-rich alpha 2-glycoprotein (LRG) present in human plasma has been determined… (More)
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