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Cord Factors

Known as: Factor, Cord, Trehalose Dimycolates, Factors, Cord 
Toxic glycolipids composed of trehalose dimycolate derivatives. They are produced by MYCOBACTERIUM TUBERCULOSIS and other species of MYCOBACTERIUM… 
National Institutes of Health

Related topics

Related topics

15 relations

Narrower (6)

6,6'-dicorynomycolyl trehalose6-mycolyl-6'-acetyltrehaloseRibi adjuvantTrehalose-6,6'-Dimycolate

Broader (1)

Immunologic Adjuvants
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Cord Factor and Peptidoglycan Recapitulate the Th17-Promoting Adjuvant Activity of Mycobacteria through Mincle/CARD9 Signaling and the Inflammasome
Although adjuvants are critical vaccine components, their modes of action are poorly understood. In this study, we investigated… 
Highly Cited
2007
Highly Cited
2007
Comparison of vesicle based antigen delivery systems for delivery of hepatitis B surface antigen.
Review
2006
Review
2006
Multiple roles of cord factor in the pathogenesis of primary, secondary, and cavitary tuberculosis, including a revised description of the pathology of secondary disease.
Tuberculosis, once thought to have been controlled, is now resurgent in many parts of the world. Many gaps exist in understanding… 
Highly Cited
2003
Highly Cited
2003
Cord factor trehalose 6,6'-dimycolate (TDM) mediates trafficking events during mycobacterial infection of murine macrophages.
The persistence of tuberculosis within pulmonary granulomatous lesions is a complex phenomenon, with bacterial survival occurring… 
Review
2001
Review
2001
Development of immunoadjuvants for immunotherapy of cancer.
Highly Cited
2001
Highly Cited
2001
Trehalose 6,6′-Dimycolate (Cord Factor) ofMycobacterium tuberculosis Induces Foreign-Body- and Hypersensitivity-Type Granulomas in Mice
ABSTRACT Granulomatous inflammation is characterized morphologically by a compact organized collection of macrophages and their… 
Highly Cited
1996
Highly Cited
1996
Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species
The surface-exposed lipids of Mycobacterium tuberculosis, Mycobacterium avium, Mycobacterium kansasii, Mycobacterium gastri… 
Highly Cited
1992
Highly Cited
1992
Risk factors for early intraventricular hemorrhage in low birth weight infants.
Highly Cited
1981
Highly Cited
1981
Isolation of a nontoxic lipid A fraction containing tumor regression activity.
Galanos-type endotoxin obtained from the heptose-less mutant of Salmonella typhimurium was converted to Lipid A by two cycles of… 
Review
1971
Review
1971
The mycobacterial cell wall
Abstract 
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