Skip to search formSkip to main contentSkip to account menu

Cord Factors

Known as: Factor, Cord, Trehalose Dimycolates, Factors, Cord 
Toxic glycolipids composed of trehalose dimycolate derivatives. They are produced by MYCOBACTERIUM TUBERCULOSIS and other species of MYCOBACTERIUM… 
National Institutes of Health

Related topics

Related topics

15 relations

Narrower (6)

6,6'-dicorynomycolyl trehalose6-mycolyl-6'-acetyltrehaloseRibi adjuvantTrehalose-6,6'-Dimycolate

Broader (1)

Immunologic Adjuvants
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1998
Review
1998
Mycobacterial lipids: a historical perspective.
Mycobacterial lipids have been studied for more than 70 years, due to the fascinating diversity of their structures and… 
1986
1986
Antitumor effect of a synthetic cord factor, 6,6'-di-O-decanoyl-alpha,alpha-trehalose (SS554), in mice.
The antitumor effect on Meth-A fibrosarcoma in BALB/c mice of a synthetic cord factor, 6,6'-di-O-decanoyl-alpha,alpha-trehalose… 
1983
1983
Enhancement of in vitro and in vivo antitumor activity by cord factor (6-6'-dimycolate of trehalose) administered suspended in saline.
The antitumor activity of trehalose-6,6'-dimycolate (TDM) dispersed in saline was studied in vitro and in vivo. In vitro… 
1982
1982
Interstitial and hemorrhagic pneumonitis induced by mycobacterial trehalose dimycolate.
Intraperitoneal injections of cord factor (trehalose dimycolate, TDM) provides a model for interstitial and hemorrhagic lung… 
Highly Cited
1980
Highly Cited
1980
Induction of resistance to Schistosoma mansoni by natural cord factor and synthetic lower homologues.
Resistance to schistosomiasis in mice can be acquired either specifically, by primary infection with Schistosoma mansoni, or… 
1979
1979
Influence of oil and Tween concentrations on enhanced endotoxin lethality in mice pretreated with emulsified trehalose-6,6'-dimycolate (cord factor)
Susceptibility to the lethal toxicity of endotoxin in mice pretreated with emulsified trehalose-6,6'-dimycolate was enhanced by… 
1979
1979
Induction of cell-mediated immunity to Mycobacterium leprae in guinea pigs
Guinea pigs immunized with intact or disrupted armadillo-grown human Mycobacterium leprae administered in aqueous or oil vehicles… 
1976
1976
Failure of trehalose-6,6'-dimycolate (P3 or cord factor) to enhance endotoxin lethality in mice
The increased endotoxin lethality in mice pretreated with BCG was not observed in mice pretreated with trehalose-6,6'-dimycolate… 
1975
1975
The adjuvant activity of a non-toxic, water-soluble glycopeptide present in large quantities in the culture filtrate of Mycobacterium tuberculosis strain DT.
A water-soluble mycobacterial glycopeptide was obtained in large quantities from the culture supernatant fluid of M. tuberculosis… 
1972
1972
Role of Cord Factor (Trehalose-6, 6′-Dimycolate) in Allergic Granuloma Formation in Rabbits
The role of cord factor in BCG-induced pulmonary granulomas and local pulmonary delayed hypersensitivity (DH) was evaluated. Cord…