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Copper Cu 64-ATSM

Known as: (64)Cu-ATSM, Copper-64-diacetyl-bis(N4-methylthiosemicarbazone) 
A radioconjugate consisting of a lipophilic copper(II)bis(thiosemicarbazone) labeled with the positron- and beta-emitting isotope (64)Cu with hypoxia… Expand
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
BACKGROUND AND PURPOSE: Hypoxic tissue evaluation in glioma is important for predicting treatment response and establishing… Expand
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Highly Cited
2008
Highly Cited
2008
Tumor uptake of copper(II)-diacetyl-bis(N4-methylthiosemicarbazone) (copper-ATSM), a hypoxia-targeting radiopharmaceutical… Expand
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Highly Cited
2008
Highly Cited
2008
INTRODUCTION Copper(II)-diacetyl-bis(N(4)-methylthiosemicarbazone), or Cu-ATSM, a hypoxia imaging agent, has been shown to be… Expand
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Highly Cited
2006
Highly Cited
2006
UNLABELLED Cu-Diacetyl-bis(N(4)-methylthiosemicarbazone) (Cu-ATSM) is a recently developed PET imaging agent for tumor hypoxia… Expand
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Highly Cited
2005
Highly Cited
2005
PURPOSE To compare two potential positron emission tomography (PET) tracers of tumor hypoxia in an animal model. METHODS AND… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Cu-diacetyl-bis(N(4)-methylthiosemicarbazone) [Cu-ATSM] is a potential marker for tumor hypoxia that has been under… Expand
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Highly Cited
2002
Highly Cited
2002
We have used copper-64-pyruvaldehyde-bis(N4-methylthiosemicarbazone) (64Cu–PTSM) to radiolabel cells ex vivo for in vivo positron… Expand
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Highly Cited
2001
Highly Cited
2001
Systemic administration of hypoxia-selective (64)Cu-diacetyl-bis(N(4)-methylthiosemicarbazone) ((64)Cu-ATSM) has increased… Expand
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Highly Cited
2000
Highly Cited
2000
Abstract62Cu labeled diacetyl-bis(N4-methylthiosemicarbazone) (62Cu-ATSM) has been proposed as a generator-produced, positron… Expand
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Highly Cited
1997
Highly Cited
1997
UNLABELLED An ideal hypoxia imaging agent should have high membrane permeability for easy access to intracellular mitochondria… Expand
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