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Conventional Dendritic Cell

Known as: Myeloid Dendritic Cell, mDC, cDC 
A subset of dendritic cells that are derived from myeloid precursors. They express toll-like receptors 2 and 4 and secrete interleukin-12.
National Institutes of Health

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Related topics

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Hematopoietic and Lymphoid TissueImmune system

Papers overview

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Highly Cited
2010
Highly Cited
2010
Diesel Exhaust Particle-Treated Human Bronchial Epithelial Cells Upregulate Jagged-1 and OX40 Ligand in Myeloid Dendritic Cells via Thymic Stromal Lymphopoietin
Ambient particulate matter, including diesel exhaust particles (DEP), promotes the development of allergic disorders. DEP… 
Highly Cited
2009
Highly Cited
2009
Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes.
Highly Cited
2008
Highly Cited
2008
Cutting Edge: Central Nervous System Plasmacytoid Dendritic Cells Regulate the Severity of Relapsing Experimental Autoimmune Encephalomyelitis1
Plasmacytoid dendritic cells (pDCs) have both stimulatory and regulatory effects on T cells. pDCs are a major CNS-infiltrating… 
Highly Cited
2005
Highly Cited
2005
Effect of gemcitabine on immune cells in subjects with adenocarcinoma of the pancreas
Effects of gemcitabine (Gemzar) on immune cells were examined in pancreas cancer patients to determine whether it was… 
Review
2005
Review
2005
Chemokines and their receptors in the pathogenesis of allergic asthma: progress and perspective
Purpose of review The importance of chemokines and their receptors to development and maintenance of allergic asthma is reflected… 
Review
2002
Review
2002
Regulation of macrophage-derived chemokine (MDC, CCL22) production.
Macrophage-derived chemokine (MDC, CCL22) is a member of the CC-chemokine family and is composed of 69 amino acid residues. MDC… 
Highly Cited
2001
Highly Cited
2001
Dendritic cells as a major source of macrophage‐derived chemokine/CCL22 in vitro and in vivo
Macrophage‐derived chemokine (MDC)/CCL22 is a CC chemokine active on dendritic cells (DC), NK cells and Th2 lymphocytes. The… 
Highly Cited
2000
Highly Cited
2000
Chemokines define distinct microenvironments in the developing thymus
During thymus development, prothymocytes home to the thymus where they migrate as maturing thymocytes from the cortex to the… 
Highly Cited
1999
Highly Cited
1999
Distinct patterns and kinetics of chemokine production regulate dendritic cell function
Dendritic cells (DC) have been showed to both produce and respond to chemokines. To understand how this may impact on DC function… 
Highly Cited
1998
Highly Cited
1998
STCP-1 (MDC) CC chemokine acts specifically on chronically activated Th2 lymphocytes and is produced by monocytes on stimulation with Th2 cytokines IL-4 and IL-13.
STCP-1 stimulated T cell chemoattractant protein-1 (STCP-1) (macrophage-derived chemokine; MDC), a recently described CC… 
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