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Consomic Strain

Known as: Chromosome Substitution Strain, Consomic Strain/Chromosome Substitution Strain 
Strains derived by repeated backcrossing while maintaining one whole chromosome genetically different from the background strain. (JAX IMSR glossary)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
High-Resolution Maps of Mouse Reference Populations
Genetic reference panels are widely used to map complex, quantitative traits in model organisms. We have generated new high… 
2014
2014
Salt-induced epithelial-to-mesenchymal transition in Dahl salt-sensitive rats is dependent on elevated blood pressure.
  • Y. WangJ. Mu Z. Yuan
  • Brazilian journal of medical and biological…
  • 2014
  • Corpus ID: 2139597
Dietary salt intake has been linked to hypertension and cardiovascular disease. Accumulating evidence has indicated that salt… 
2014
2014
Salt-induced epithelial-to-mesenchymal transition in Dahl salt-sensitive rats is dependent on elevated blood pressure
  • Y. WangJ. Mu Z. Yuan
  • Brazilian journal of medical and biological…
  • 2014
  • Corpus ID: 10703143
Dietary salt intake has been linked to hypertension and cardiovascular disease. Accumulating evidence has indicated that salt… 
2013
2013
Genetic resistance to liver fibrosis on A/J mouse chromosome 17.
BACKGROUND Because the histological and biochemical progression of liver disease is similar in alcoholic steatohepatitis (ASH… 
2012
2012
Congenic dissection of a major QTL for methamphetamine sensitivity implicates epistasis
We previously used the C57BL/6J (B6) × A/J mouse chromosome substitution strain (CSS) panel to identify a major quantitative… 
2008
2008
Sex-specific differences in chromosome-dependent regulation of vascular reactivity in female consomic rat strains from a SSxBN cross.
High-throughput studies in the Medical College of Wisconsin Program for Genomic Applications (Physgen) were designed to link… 
2008
2008
Multigenic factors associated with a hydrocephalus-like phenotype found in inter-subspecific consomic mouse strains
Hydrocephalus is a significant clinical condition in humans and is known to be a multifactorial neurologic disorder. It has been… 
2005
2005
Interacting genetic loci cause airway hyperresponsiveness.
Airway hyperresponsiveness (AHR) is a key physiological component of asthma, and the genetic basis of this complex trait has… 
Highly Cited
2003
Highly Cited
2003
Chromosome substitution strains: some quantitative considerations for genome scans and fine mapping
A chromosome substitution strain (CSS) is an inbred strain in which one chromosome has been substituted from a different inbred… 
2003
2003
An autoimmune diabetes locus (Idd21) on mouse Chromosome 18
Twenty-four named Idd loci that contribute to the development of autoimmune diabetes in the nonobese diabetic (NOD) mouse have… 
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