Congenital absence of thymus

The thymus is essential for T-cell development. Here, we focus on the role of the transcription factor Foxn1 in the development… Expand

Deletion of chromosome 22q11, the most common microdeletion detected in humans, is associated with a life-threatening array of… Expand

The molecular characteristics of the nude phenotype (alopecia and thymic aplasia) in humans and rodents are unknown. The nude… Expand

To investigate molecular and clinical aspects of conotruncal anomaly face (CAF), we studied the correlation between deletion size… Expand

Neuronal changes in the brain of a Rett syndrome patient were examined in a frontal lobe biopsy performed at age 3 years and in… Expand

Despite animal vitamin A congener teratogenicity in animal studies since 1954, striking human findings only arose in 1983… Expand

Despite animal vitamin A congener teratogenicity in animal studies since 1954, striking human findings only arose in 1983… Expand

SummaryPartial monosomy of 22q due to an unbalanced 4;22 translocation was seen in a 2-month-old male with Type I truncus… Expand

Treatment with desoxycorticosterone acetate (DOCA) and 1 per cent saline as drinking water for 21 days caused a significant and… Expand

creasing interest in the function of the thymus and its relationship to clinical disease. The thymus has been shown to have a… Expand