Thymus Gland

Known as: Thymus, Chest>Thymus gland, Thymus Glands 
A bi-lobed organ surrounded by a connective tissue capsule. It is located in the upper anterior portion of the chest, behind the sternum. It is… (More)
National Institutes of Health

Related topics

Related topics

45 relations
Acute Thymic InvolutionBenign neoplasm of thymusClinical Data Interchange Standards Consortium TerminologyDLEU1 Protein
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Broader (3)

Anterior mediastinumCorticomedullary organLymphoid Tissue

Papers overview

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Highly Cited
2004
Highly Cited
2004
Medullary Epithelial Cells of the Human Thymus Express a Highly Diverse Selection of Tissue-specific Genes Colocalized in Chromosomal Clusters
Promiscuous expression of tissue-specific self-antigens in the thymus imposes T cell tolerance and protects from autoimmune… (More)
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Highly Cited
2003
Highly Cited
2003
Flt3 Ligand Regulates Dendritic Cell Development from Flt3+ Lymphoid and Myeloid-committed Progenitors to Flt3+ Dendritic Cells In Vivo
Stimulation of Flt3 receptor tyrosine kinase through its cognate ligand expands early hematopoietic progenitor and dendritic… (More)
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Review
2002
Review
2002
The thymus gland is a target in malnutrition
Malnutrition, secondary to deficiency in uptake of proteins, metal elements or vitamins, consistently results in changes in the… (More)
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Highly Cited
2002
Highly Cited
2002
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
During lymphocyte development, the assembly of genes coding for antigen receptors occurs by the combinatorial linking of gene… (More)
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Highly Cited
2000
Highly Cited
2000
Lymphocyte Cc Chemokine Receptor 9 and Epithelial Thymus-Expressed Chemokine (Teck) Expression Distinguish the Small Intestinal Immune Compartment
The immune system has evolved specialized cellular and molecular mechanisms for targeting and regulating immune responses at… (More)
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Highly Cited
1998
Highly Cited
1998
Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands.
The thymus, thyroid, and parathyroid glands in vertebrates develop from the pharyngeal region, with contributions both from… (More)
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Highly Cited
1997
Highly Cited
1997
CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4.
Murine CD1 has been implicated in the development and function of an unusual subset of T cells, termed natural T (NT) cells, that… (More)
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Highly Cited
1995
Highly Cited
1995
Thyroid cancer after exposure to external radiation: a pooled analysis of seven studies.
The thyroid gland of children is especially vulnerable to the carcinogenic action of ionizing radiation. To provide insights into… (More)
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Highly Cited
1995
Highly Cited
1995
The role of Hoxa-3 in mouse thymus and thyroid development.
Targeted disruption of Hoxa-3 results in a number of regionally restricted defects in tissues and structures derived from or… (More)
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Highly Cited
1984
Highly Cited
1984
Dependence of thymus development on derivatives of the neural crest.
Elimination of limited areas of the cephalic neural crest in stage 9 or 10 chick embryos markedly reduced the size of the thymus… (More)
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