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Members of the Runx and MYC families have been implicated as collaborating oncogenes. The mechanism of this potent collaboration… Expand Mucins are high molecular weight glycoproteins that are heavily glycosylated with many oligosaccharide side chains linked O… Expand p53 is a tumor suppressor gene that is mutated in many human malignancies, including gastric cancer. It remains unclear why… Expand BACKGROUND Eradication of Barrett's mucosa by thermal or photoablation combined with high doses of proton pump inhibitors is a… Expand The pathways to lymphoid neoplasia have been explored in a number of transgenic models. Because B lymphoid malignancies often… Expand Three lines of transgenic mice were produced that develop pancreatic neoplasms as a consequence of expression of an elastase I… Expand Adriamycin-resistant (AdrR) human breast cancer cells have been selected which exhibit cross-resistance to a wide range of anti… Expand The effect of dietary exposure to synthetic estrogens on hepatocarcinogenesis was evaluated. Diethylnitrosamine-initiated and 0… Expand Current awareness of the importance of environmental factors such as diet in the etiology of human cancer has stimulated renewed… Expand This paper reviews the hormonal factors involved in the events leading to formation of mammary tumors in mice. Studies on the… Expand