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Complex Karyotype

Karyotype with at least three chromosomal aberrations.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Ibrutinib is active in patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL). In patients treated with… 
Highly Cited
2012
Highly Cited
2012
To assess the frequency of TP53 alterations and their correlation with other genetic changes and outcome in acute myeloid… 
Highly Cited
2012
Highly Cited
2012
DNMT3A mutations and response to the hypomethylating agent decitabine in acute myeloid leukemia 
Highly Cited
2009
Highly Cited
2009
TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor… 
Highly Cited
2008
Highly Cited
2008
PURPOSE To investigate the prognostic value of various cytogenetic components of a complex karyotype in acute myeloid leukemia… 
Review
2008
Review
2008
  • K. Mrózek
  • Seminars in oncology
  • 2008
  • Corpus ID: 27179812
Patients with acute myeloid leukemia (AML) harboring three or more acquired chromosome aberrations in the absence of the… 
Review
2007
Review
2007
Pretreatment cytogenetics is a known predictor of outcome in hematologic malignancies. However, its usefulness in adult acute… 
Highly Cited
2002
Highly Cited
2002
We analyzed prospectively 1213 adults with de novo acute myeloid leukemia (AML) to ascertain the prognostic impact of cytogenetic… 
Highly Cited
2001
Highly Cited
2001
PURPOSE To study mutations and loss of heterozygosity (LOH) of p53 in therapy-related myelodysplasia (t-MDS) and acute myeloid…