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Complex Karyotype

Karyotype with at least three chromosomal aberrations.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Ibrutinib is active in patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL). In patients treated with… Expand
Highly Cited
2012
Highly Cited
2012
To assess the frequency of TP53 alterations and their correlation with other genetic changes and outcome in acute myeloid… Expand
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Highly Cited
2012
Highly Cited
2012
DNMT3A mutations and response to the hypomethylating agent decitabine in acute myeloid leukemia 
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Highly Cited
2010
Highly Cited
2010
To identify cytogenetic risk factors predicting outcome in children with advanced myelodysplastic syndrome, overall survival of… Expand
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Highly Cited
2009
Highly Cited
2009
TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor… Expand
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Highly Cited
2008
Highly Cited
2008
PURPOSE To investigate the prognostic value of various cytogenetic components of a complex karyotype in acute myeloid leukemia… Expand
Review
2008
Review
2008
  • K. Mrózek
  • Seminars in oncology
  • 2008
  • Corpus ID: 27179812
Patients with acute myeloid leukemia (AML) harboring three or more acquired chromosome aberrations in the absence of the… Expand
Highly Cited
2002
Highly Cited
2002
We analyzed prospectively 1213 adults with de novo acute myeloid leukemia (AML) to ascertain the prognostic impact of cytogenetic… Expand
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Highly Cited
2001
Highly Cited
2001
PURPOSE To study mutations and loss of heterozygosity (LOH) of p53 in therapy-related myelodysplasia (t-MDS) and acute myeloid… Expand
Highly Cited
2001
Highly Cited
2001
The clinical significance of complex chromosome aberrations for adults with acute myeloid leukaemia (AML) was assessed in 920… Expand