FAQ

Complement component C4a

Known as: Complement C4a [Chemical/Ingredient], Complement C4a, Complement, C4a 
The smaller fragment formed when complement C4 is cleaved by COMPLEMENT C1S. It is an anaphylatoxin that causes symptoms of immediate… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2018
02419812018

Related topics

Related topics

12 relations
C4A geneComplement C4a:MCnc:Pt:Plas:QnProcess of secretionagonists
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Narrower (2)

Complement Component 4a Deficiencycomplement C4a, des-Arg

Broader (1)

Immunologic Factors

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Complement component C4a
physiological aspects
chemical synthesis
Immunologic Factors
C4A gene
standards characteristics

Papers overview

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2012
2012
Pentachlorophenol hydroxylase, a poorly functioning enzyme required for degradation of pentachlorophenol by Sphingobium chlorophenolicum.
Several strains of Sphingobium chlorophenolicum have been isolated from soil that was heavily contaminated with pentachlorophenol… (More)
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2011
2011
Stabilization of C4a-hydroperoxyflavin in a two-component flavin-dependent monooxygenase is achieved through interactions at flavin N5 and C4a atoms.
p-Hydroxyphenylacetate (HPA) 3-hydroxylase is a two-component flavin-dependent monooxygenase. Based on the crystal structure of… (More)
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2011
2011
Interactions with the substrate phenolic group are essential for hydroxylation by the oxygenase component of p-hydroxyphenylacetate 3-hydroxylase.
p-Hydroxyphenylacetate (HPA) 3-hydroxylase is a two-component flavoprotein monooxygenase that catalyzes the hydroxylation of p… (More)
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2009
2009
Crystallographic, spectroscopic, and computational analysis of a flavin C4a-oxygen adduct in choline oxidase.
Flavin C4a-OO(H) and C4a-OH adducts are critical intermediates proposed in many flavoenzyme reaction mechanisms, but they are… (More)
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2008
2008
Kinetic mechanism of phenylacetone monooxygenase from Thermobifida fusca.
Phenylacetone monooxygenase (PAMO) from Thermobifida fusca is a FAD-containing Baeyer-Villiger monooxygenase (BVMO). To elucidate… (More)
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2006
2006
Analysis of the Primary Photocycle Reactions Occurring in the Light, Oxygen, and Voltage Blue-Light Receptor by Multiconfigurational Quantum-Chemical Methods.
The photocycle reactions occurring between the flavin mononucleotide cofactor and the reactive cysteine residue in the blue-light… (More)
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2001
2001
Mechanistic studies of cyclohexanone monooxygenase: chemical properties of intermediates involved in catalysis.
Cyclohexanone monooxygenase (CHMO), a bacterial flavoenzyme, carries out an oxygen insertion reaction on cyclohexanone to form a… (More)
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1993
1993
On the reaction mechanism of phenol hydroxylase. New information obtained by correlation of fluorescence and absorbance stopped flow studies.
Steps in the hydroxylation pathway of the flavoprotein phenol hydroxylase with resorcinol as substrate have been studied by a… (More)
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1988
1988
Accentuated formation of the terminal C5b-9 complement complex in patient plasma precedes development of the adult respiratory distress syndrome.
Extensive studies have been conducted to determine the pathogenesis of the adult respiratory distress syndrome (ARDS) by… (More)
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1981
1981
Complete primary structure of human C4a anaphylatoxin.
C4a anaphylatoxin is derived from the fourth component (C4) of the blood complement system. The C4 alpha-chain is selectively… (More)
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