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Complement C5a, des-Arginine

Known as: des-Arg, C5a, C5 a, des Arg, C5a, des-Arginine 
A derivative of complement C5a, generated when the carboxy-terminal ARGININE is removed by CARBOXYPEPTIDASE B present in normal human serum. C5a des… 
National Institutes of Health

Related topics

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Broader (1)

Immunologic Factors
Process of secretionagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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Highly Cited
2016
Highly Cited
2016
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
Review
2011
Review
2011
Histone arginine methylation
Highly Cited
2007
Highly Cited
2007
JMJD6 Is a Histone Arginine Demethylase
Arginine methylation occurs on a number of proteins involved in a variety of cellular functions. Histone tails are known to be… 
Highly Cited
2006
Highly Cited
2006
Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells
Blimp1, a transcriptional repressor, has a crucial role in the specification of primordial germ cells (PGCs) in mice at embryonic… 
Highly Cited
2004
Highly Cited
2004
Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells.
The results described herein support a mechanistic hypothesis for how guanidine-rich transporters attached to small cargos (MW ca… 
Highly Cited
1996
Highly Cited
1996
Activation of a recombinant membrane type 1‐matrix metalloproteinase (MT1‐MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)‐2
Highly Cited
1992
Highly Cited
1992
Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin.
Proteolytic cleavage of the protective antigen (PA) protein of anthrax toxin at residues 164-167 is necessary for toxic activity… 
Highly Cited
1985
Highly Cited
1985
Primary structures of three human neutrophil defensins.
The primary structures of three human neutrophil antimicrobial peptides (HNP) were determined. The peptides, HNP-1, HNP-2, and… 
Highly Cited
1981
Highly Cited
1981
Complement activation during cardiopulmonary bypass: evidence for generation of C3a and C5a anaphylatoxins.
We observed complement activation in 15 adults undergoing total cardiopulmonary bypass. Plasma levels of C3a were significantly… 
Highly Cited
1978
Highly Cited
1978
Chemotactic response to human C3a and C5a anaphylatoxins. I. Evaluation of C3a and C5a leukotaxis in vitro and under stimulated in vivo conditions.
Peptides C3a and C5a, also known as anaphylatoxins, are derived from C components C3 and C5 and have previously been reported… 
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