Complement C3 Convertase, Classical Pathway

Known as: Classical Pathway C3 Convertase, C3 Convertase (C4b2a), Classical C3 Convertase 
A serine protease that cleaves multiple COMPLEMENT 3 into COMPLEMENT 3A (anaphylatoxin) and COMPLEMENT 3B in the CLASSICAL COMPLEMENT ACTIVATION… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2013
012319802013

Papers overview

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2007
2007
Activation of component C3 is central to the pathways of complement and leads directly to neutralization of pathogens and… (More)
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1992
1992
A major protein secreted by vaccinia virus-infected cells has structural similarity to the super-family of complement-control… (More)
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1992
1992
In general, C4A allotypes of human C4 show one-fourth to one-third the hemolytic activity of C4B allotypes. An exception to this… (More)
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1992
1992
A unique thioester bond, formed between the side chains of neighboring C and Q residues, is present in complement components C3… (More)
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1987
1987
The fluid phase C3 convertase of the alternative pathway of human complement activation has been constructed from the isolated C3… (More)
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1987
1987
C4 nephritic factor (C4NeF) was found in the serum of a patient with chronic glomerulonephritis, whose C3 level was quite low… (More)
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1986
1986
The formation of classical C3 convertase of complement and its regulation by C4b-binding protein (C4bp) were studied using two… (More)
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1985
1985
The classical pathway C3 convertase (C4b2a) is regulated by the action of two components. C4 binding protein (C4bp) accelerates… (More)
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1981
1981
A protein with decay-accelerating activity for the classical C3 convertase, C4b2a, has been isolated on the basis of this… (More)
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1980
1980
The assembly of the classical pathway C3 convertase in the fluid phase has been studied. The enzyme is assembled from C2 and C4… (More)
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