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Co-Repressor Proteins

Known as: Co Repressors, Corepressors, Corepressor Proteins 
A subclass of repressor proteins that do not directly bind DNA. Instead, co-repressors generally act via their interaction with DNA-BINDING PROTEINS… 
National Institutes of Health

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19 relations

Narrower (11)

C1D protein, humanCoREST2 protein, ratInsv protein, DrosophilaMIDEAS protein, human
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

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Highly Cited
2005
Highly Cited
2005
Myc represses transcription through recruitment of DNA methyltransferase corepressor
The Myc transcription factor is an essential mediator of cell growth and proliferation through its ability to both positively and… 
Review
2002
Review
2002
CtBP, an unconventional transcriptional corepressor in development and oncogenesis.
Highly Cited
2001
Highly Cited
2001
The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux
Cytochrome P450 3A4 is an important mediator of drug catabolism that can be regulated by the steroid and xenobiotic receptor (SXR… 
Highly Cited
2001
Highly Cited
2001
The p65 (RelA) Subunit of NF-κB Interacts with the Histone Deacetylase (HDAC) Corepressors HDAC1 and HDAC2 To Negatively Regulate Gene Expression
ABSTRACT Regulation of NF-κB transactivation function is controlled at several levels, including interactions with coactivator… 
Highly Cited
1999
Highly Cited
1999
Molecular determinants of nuclear receptor-corepressor interaction.
Retinoic acid and thyroid hormone receptors can act alternatively as ligand-independent repressors or ligand-dependent activators… 
Highly Cited
1999
Highly Cited
1999
Mechanism of corepressor binding and release from nuclear hormone receptors.
The association of transcription corepressors SMRT and N-CoR with retinoid and thyroid receptors results in suppression of basal… 
Review
1999
Review
1999
Sin Meets NuRD and Other Tails of Repression
Highly Cited
1998
Highly Cited
1998
Homeodomain-interacting Protein Kinases, a Novel Family of Co-repressors for Homeodomain Transcription Factors*
A novel family of cofactors that differentially interact with homeoproteins have been identified via a yeast two-hybrid screen… 
Highly Cited
1998
Highly Cited
1998
Nuclear Receptor DAX-1 Recruits Nuclear Receptor Corepressor N-CoR to Steroidogenic Factor 1
ABSTRACT The orphan nuclear receptor steroidogenic factor 1 (SF-1) is a critical developmental regulator in the urogenital ridge… 
Review
1997
Review
1997
Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action.
Steroid/thyroid hormone receptors are ligand-dependent transcription factors that regulate diverse aspects of growth, development… 
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