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Co 101244

Known as: Co-101244 
National Institutes of Health

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PD 174494

Papers overview

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2014
2014
Unprecedented Therapeutic Potential with a Combination of A2A/NR2B Receptor Antagonists as Observed in the 6-OHDA Lesioned Rat Model of Parkinson's Disease
In Parkinson's disease, the long-term use of dopamine replacing agents is associated with the development of motor complications… 
2012
2012
Impacts of Female Gonadal Hormones on Pelvic Organ-related Neural Plasticity
2012
2012
Ifenprodil, a NR2B-selective antagonist of NMDA receptor, inhibits reverse Na+/Ca2+ exchanger in neurons
2012
2012
Ifenprodil , a NR 2 B-selective antagonist of NMDA receptor , inhibits reverse Na þ / Ca 2 þ exchanger in neurons
Glutamate-induced delayed calcium dysregulation (DCD) is causally linked to excitotoxic neuronal death. The mechanisms of DCD are… 
2009
2009
Colon mustard oil instillation induced cross-organ reflex sensitization on the pelvic–urethra reflex activity in rats
2009
2009
Estrogen-dependent facilitation on spinal reflex potentiation involves the Cdk5/ERK1/2/NR2B cascade in anesthetized rats.
Cyclin-dependent kinase-5 (Cdk5), a proline-directed serine/threonine kinase, may alter pain-related neuronal plasticity by… 
2008
2008
Orexin-A modulates glutamatergic NMDA-dependent spinal reflex potentiation via inhibition of NR2B subunit.
Glucose-sensitive neurons in the lateral hypothalamic area produce orexin-A (OxA) as well as orexin-B (OxB) and send their axons… 
2004
2004
NR2B receptors are involved in the mediation of spinal segmental reflex potentials but not in the cumulative motoneuronal depolarization in vitro
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