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Immunoglobulin heavy chain (IGH) clonality testing by next-generation sequencing (NGS) offers unique advantages over current low… Expand BackgroundIntratumor heterogeneity has been demonstrated in several cancer types, following a model of branched evolution. It is… Expand Glutaminyl-tRNA synthetase (QARS) deficiency has been described to be a cause of a neurodegenerative disorder associated with… Expand Objectives: Recent studies using next-generation sequencing (NGS) analysis disclosed the importance of the intrinsic activation… Expand The objective of our study was to describe the molecular support of carbapenem resistance from randomly selected clinical… Expand Gene transfer to hematopoietic stem cells with integrating vectors not only allows sustained correction of monogenic diseases but… Expand PCR-based immunoglobulin (Ig)/T-cell receptor (TCR) clonality testing in suspected lymphoproliferations has largely been… Expand Background: Refractory celiac disease (RCD) is a preneoplastic condition as many patients develop an enteropathy-type T-cell… Expand BACKGROUND
A sensitive micromethod for T-cell receptor (TCR) analysis is needed for clonality analysis of renal allograft… Expand Determination of clonality in B-cell lymphomas is a useful diagnostic adjunct. In situ hybridization (ISH) for the detection of K… Expand