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Clindamycin

Known as: Clindamicina, Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside, clindamicin 
A semisynthetic broad spectrum antibiotic produced by chemical modification of the parent compound lincomycin. Clindamycin dissociates peptidyl-tRNA… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
ABSTRACT Antibiotic-induced changes in the intestinal microbiota predispose mammalian hosts to infection with antibiotic… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly recognized in infections among persons in the… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Recent reports suggest that the rate and severity of Clostridium difficile-associated disease in the United States are… Expand
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Highly Cited
2003
Highly Cited
2003
We report a case of a surgical site infection caused by clindamycin-susceptible, erythromycin-resistant methicillin-resistant… Expand
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Highly Cited
2003
Highly Cited
2003
ABSTRACT Resistance to macrolides in staphylococci may be due to active efflux (encoded by msrA) or ribosomal target modification… Expand
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Review
2002
Review
2002
  • R. Leclercq
  • Clinical infectious diseases : an official…
  • 2002
  • Corpus ID: 14714107
Resistance to macrolides and lincosamides is increasingly reported in clinical isolates of gram-positive bacteria. The… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Large outbreaks of diarrhea caused by a newly recognized strain of Clostridium difficile occurred in four hospitals… Expand
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Highly Cited
1996
Highly Cited
1996
Macrolide-resistant Streptococcus pyogenes isolates from Finland, Australia, and the United Kingdom and, more recently… Expand
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Review
1990
Review
1990
  • B. Murray
  • Clinical Microbiology Reviews
  • 1990
  • Corpus ID: 735451
Enterococci are important human pathogens that are increasingly resistant to antimicrobial agents. These organisms were… Expand
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Highly Cited
1988
Highly Cited
1988
We investigated the relative efficacies of penicillin, clindamycin, and erythromycin in a mouse model of myositis due to… Expand
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