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Circulating Tumor Cell Count

Known as: CTC, Circulating Tumor Cells 
The determination of the amount of circulating tumor cells present in a sample.
National Institutes of Health

Related topics

Related topics

4 relations
CDISC SDTM Laboratory Test Terminology by CodeCDISC SDTM Laboratory Test Terminology by NameCirculating Neoplastic CellsClinical Data Interchange Standards Consortium Terminology

Papers overview

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Review
2019
Review
2019
Heterogeneity in Circulating Tumor Cells: The Relevance of the Stem-Cell Subset
The release of circulating tumor cells (CTCs) into vasculature is an early event in the metastatic process. The analysis of CTCs… Expand
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Review
2018
Review
2018
Understanding tumor ecosystems by single-cell sequencing: promises and limitations
Cellular heterogeneity within and across tumors has been a major obstacle in understanding and treating cancer, and the complex… Expand
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Review
2018
Review
2018
The biology and role of CD44 in cancer progression: therapeutic implications
CD44, a non-kinase transmembrane glycoprotein, is overexpressed in several cell types including cancer stem cells and frequently… Expand
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Highly Cited
2012
Highly Cited
2012
Clinical significance and molecular characteristics of circulating tumor cells and circulating tumor microemboli in patients with small-cell lung cancer.
PURPOSE Circulating tumor cells (CTCs) may have utility as surrogate biomarkers and "virtual" biopsies. We report the clinical… Expand
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Highly Cited
2009
Highly Cited
2009
Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients
IntroductionThe persistence of circulating tumor cells (CTC) in breast cancer patients might be associated with stem cell like… Expand
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Highly Cited
2008
Highly Cited
2008
Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer.
PURPOSE As treatment options expand for metastatic colorectal cancer (mCRC), a blood marker with a prognostic and predictive role… Expand
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Highly Cited
2006
Highly Cited
2006
Circulating Tumor Cells at Each Follow-up Time Point during Therapy of Metastatic Breast Cancer Patients Predict Progression-Free and Overall Survival
Purpose: We reported previously that ≥5 circulating tumor cells (CTC) in 7.5 mL blood at baseline and at first follow-up in 177… Expand
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Highly Cited
2004
Highly Cited
2004
Circulating tumor cells, disease progression, and survival in metastatic breast cancer.
BACKGROUND We tested the hypothesis that the level of circulating tumor cells can predict survival in metastatic breast cancer… Expand
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Highly Cited
1993
Highly Cited
1993
Detection and viability of tumor cells in peripheral blood stem cell collections from breast cancer patients using immunocytochemical and clonogenic assay techniques.
Although peripheral blood stem cell collections (PBSC) are thought to have less tumor involvement than bone marrow (BM), the… Expand
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Highly Cited
1992
Highly Cited
1992
Use of a fluorescent redox probe for direct visualization of actively respiring bacteria.
The redox dye 5-cyano-2,3-ditolyl tetrazolium chloride (CTC) was employed for direct epifluorescent microscopic enumeration of… Expand
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