Circulating Tumor Cell Count

Known as: CTC, Circulating Tumor Cells 
The determination of the amount of circulating tumor cells present in a sample.
National Institutes of Health

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CDISC SDTM Laboratory Test Terminology by CodeCDISC SDTM Laboratory Test Terminology by NameCirculating Neoplastic CellsClinical Data Interchange Standards Consortium Terminology

Papers overview

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Highly Cited
2014
Highly Cited
2014
Circulating tumor cells and response to chemotherapy in metastatic breast cancer: SWOG S0500.
PURPOSE Increased circulating tumor cells (CTCs; five or more CTCs per 7.5 mL of whole blood) are associated with poor prognosis… (More)
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Highly Cited
2012
Highly Cited
2012
Clinical significance and molecular characteristics of circulating tumor cells and circulating tumor microemboli in patients with small-cell lung cancer.
PURPOSE Circulating tumor cells (CTCs) may have utility as surrogate biomarkers and "virtual" biopsies. We report the clinical… (More)
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Highly Cited
2012
Highly Cited
2012
Circulating miRNAs as surrogate markers for circulating tumor cells and prognostic markers in metastatic breast cancer.
PURPOSE The use of circulating tumor cells (CTC) as a prognostic marker in metastatic breast cancer (MBC) has been well… (More)
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Highly Cited
2012
Highly Cited
2012
High independent prognostic and predictive value of circulating tumor cells compared with serum tumor markers in a large prospective trial in first-line chemotherapy for metastatic breast cancer…
BACKGROUND Circulating tumor cells (CTCs) are a prognostic marker in metastatic breast cancer, but comparisons with serum tumor… (More)
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Highly Cited
2011
Highly Cited
2011
Preoperative circulating tumor cell detection using the isolation by size of epithelial tumor cell method for patients with lung cancer is a new prognostic biomarker.
PURPOSE Pathologic TNM staging is currently the best prognostic factor for non-small cell lung carcinoma (NSCLC). However, even… (More)
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Highly Cited
2009
Highly Cited
2009
Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients
The persistence of circulating tumor cells (CTC) in breast cancer patients might be associated with stem cell like tumor cells… (More)
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Highly Cited
2008
Highly Cited
2008
Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer.
PURPOSE As treatment options expand for metastatic colorectal cancer (mCRC), a blood marker with a prognostic and predictive role… (More)
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Highly Cited
2008
Highly Cited
2008
Circulating tumor cell detection predicts early metastatic relapse after neoadjuvant chemotherapy in large operable and locally advanced breast cancer in a phase II randomized trial.
PURPOSE Circulating tumor cells in blood from metastatic breast cancer patients have been reported as a surrogate marker for… (More)
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Highly Cited
2006
Highly Cited
2006
Circulating tumor cells at each follow-up time point during therapy of metastatic breast cancer patients predict progression-free and overall survival.
PURPOSE We reported previously that >or=5 circulating tumor cells (CTC) in 7.5 mL blood at baseline and at first follow-up in 177… (More)
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Highly Cited
2004
Highly Cited
2004
Circulating tumor cells, disease progression, and survival in metastatic breast cancer.
BACKGROUND We tested the hypothesis that the level of circulating tumor cells can predict survival in metastatic breast cancer… (More)
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