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Cidofovir

Known as: (S)-HPMPC, 1-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine, (S)-1-[3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine 
A synthetic, acyclic, monophosphate nucleotide analog of deoxycytidine with antiviral activity, and mostly used against cytomegalovirus (CMV). After… 
National Institutes of Health

Related topics

Related topics

13 relations
AIDS-Related Opportunistic InfectionsCidofovir:Susc:Pt:Isolate:OrdQnCidofovir:Susc:Pt:Isolate:OrdQn:GenotypingCytomegalovirus Infections

Broader (3)

Antiviral AgentsCytosineOrganophosphonates

Narrower (2)

GS 504Vistide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Development of new cytomegalovirus UL97 and DNA polymerase mutations conferring drug resistance after valganciclovir therapy in allogeneic stem cell recipients.
Review
2003
Review
2003
Statin Use and Bone Mineral Density in Renal Transplant Recipients
While statins are associated with increased bone mineral density (BMD) (1,2) and less fracture risk (3) in the general population… 
Highly Cited
2002
Highly Cited
2002
Broad-spectrum antiviral activity of PNU-183792, a 4-oxo-dihydroquinoline, against human and animal herpesviruses.
Highly Cited
1997
Highly Cited
1997
Treatment of verruca vulgaris with topical cidofovir.
To the Editor. —Cidofovir is a nucleotide analog of deoxycytidine monophosphate and has antiviral activity against a broad range… 
Review
1997
Review
1997
Therapeutic approaches to papillomavirus infections.
Highly Cited
1996
Highly Cited
1996
A canine distemper virus epidemic in Serengeti lions (Panthera leo)
Nature 379, 441–445 (1996). IN this Letter, we neglected to refer to the paper by T. C. Harder et al (Vaccine 13, 521-523; 1995… 
Review
1996
Review
1996
Acyclic nucleosides as antiviral compounds
Acyclovir is an effective drug for the treatment of HSV and VZV infections, which after phosphorylation to the triphosphate… 
Highly Cited
1992
Highly Cited
1992
Efficacy of (S)‐1‐(3‐hydroxy‐2‐phosphonylmethoxypropyl)cytosine and 9‐(1,3‐dihydroxy‐2‐propoxymethyl)guanine for the treatment of murine cytomegalovirus infection in severe combined immunodeficiency…
Mice with severe combined immunodeficiency (SCID) inoculated intraperitoneally with murine cytornegalovirus (MCMV) develop a… 
Highly Cited
1991
Highly Cited
1991
Inhibitory effect of (S)-HPMPC, (S)-HPMPA, and 2'-nor-cyclic GMP on clinical ocular adenoviral isolates is serotype-dependent in vitro.
Highly Cited
1974
Highly Cited
1974
Experimental canine distemper virus-induced lymphoid depletion.
Thirty-four gnotobiotic dogs were used to study the effects of R252 canine distemper virus (CDV) infection on the lymphoid system… 
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