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Chromosomes, Human, Pair 12

Known as: 12 chromosome, Chromosome 12 
The designation for each member of the twelfth largest human autosomal chromosome pair. Chromosome 12 spans about 143 million base pairs and… 
National Institutes of Health

Related topics

Related topics

34 relations
12qAleukemic Chronic Lymphocytic LeukemiaAtypical LipomaCSRNP2 gene

Narrower (3)

Chromosome 12, 12p trisomyChromosome 12, trisomy 12qPallister-Killian syndrome

Broader (1)

Chromosomes, Human, 6-12 and X

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Biosynthesis of Antinutritional Alkaloids in Solanaceous Crops Is Mediated by Clustered Genes
From Nasty to Tasty Some of our favorite food crops derive from wild relatives that were distasteful or even toxic. Domestication… 
Highly Cited
2000
Highly Cited
2000
Identification of an imprinted gene, Meg3/Gtl2 and its human homologue MEG3, first mapped on mouse distal chromosome 12 and human chromosome 14q
The paternal duplication of mouse distal chromosome 12 leads to late embryonal/neonatal lethality and growth promotion, whereas… 
Highly Cited
1999
Highly Cited
1999
Regulation of carotenoid biosynthesis during tomato fruit development: expression of the gene for lycopene epsilon-cyclase is down-regulated during ripening and is elevated in the mutant Delta.
The red colour of tomato (Lycopersicon esculentum) fruits is provided by the carotenoid pigment lycopene whose concentration… 
Review
1997
Review
1997
Regulation of mammalian acetyl-coenzyme A carboxylase.
Long-chain fatty acids are involved in all aspects of cellular structure and function. For controlling amounts of fatty acids… 
Highly Cited
1997
Highly Cited
1997
Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12.
CONTEXT Four genetic loci have been identified as contributing to Alzheimer disease (AD), including the amyloid precursor protein… 
Highly Cited
1996
Highly Cited
1996
Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families
Non–insulin dependent diabetes mellitus (NIDDM) affects more than 100 million people worldwide1,2 and is associated with severe… 
Highly Cited
1995
Highly Cited
1995
The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion.
Analysis of a growing number of chromosomal translocations in human tumors have shown that they frequently result in gene fusions… 
Highly Cited
1993
Highly Cited
1993
Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas.
The 34-kilodalton cyclin-dependent kinase, p34cdk4, is a major catalytic subunit of mammalian D-type cyclins, which act during… 
Highly Cited
1990
Highly Cited
1990
Myf‐6, a new member of the human gene family of myogenic determination factors: evidence for a gene cluster on chromosome 12.
The Myf‐6 gene, a novel member of the human gene family of muscle determination factors has been detected by its highly conserved… 
Highly Cited
1985
Highly Cited
1985
Human von Willebrand factor (vWF): isolation of complementary DNA (cDNA) clones and chromosomal localization.
Human factor VIII--von Willebrand factor (vWF) is a large, multimeric glycoprotein that plays a central role in the blood… 
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