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Chromosome 8, trisomy

Known as: chromosome 8 trisomy syndrome, TRISOMY 8 SYNDROME, Chromosome 8 duplication 
A chromosomal abnormality consisting of the presence of a third copy of chromosome 8 in somatic cells.
National Institutes of Health

Related topics

Related topics

29 relations
Acute Myeloid Leukemia with Minimal DifferentiationBlast PhaseChest Wall FibromatosisDensely Granulated Pituitary Gland Lactotroph Adenoma

Broader (2)

Chromosomes, Human, Pair 8Trisomy

Papers overview

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Highly Cited
2010
Highly Cited
2010
FISH and SNP-A karyotyping in myelodysplastic syndromes: improving cytogenetic detection of del(5q), monosomy 7, del(7q), trisomy 8 and del(20q).
Highly Cited
2006
Highly Cited
2006
CD34 cells from patients with trisomy 8 myelodysplastic syndrome (MDS) express early apoptotic markers but avoid programmed cell death by up-regulation of antiapoptotic proteins.
CD34 cells from patients with trisomy 8 myelodysplastic syndrome (MDS) are distinguished from other MDS cells and from normal… 
1995
1995
Acute leukemia and the transient myeloproliferative disorder associated with Down syndrome: morphologic, immunophenotypic and cytogenetic manifestations.
Individuals with Down syndrome have an increased incidence of leukemia compared to the general population. In addition, Down… 
Review
1994
Review
1994
Trisomy 8 syndrome owing to isodicentric 8p chromosomes: regional assignment of a presumptive gene involved in corpus callosum development.
Two patients with trisomy 8 syndrome owing to an isodicentric 8p;8p chromosome are described. Case 1 had a 46,XX/46,XX,-8,+idic(8… 
1994
1994
Myelodysplasia in a patient with pre‐existing paroxysmal nocturnal haemoglobinuria: a clonal disease originating from within a clonal disease
SUMMARY. Paroxysmal nocturnal haemoglobinuria (PNH) is an acquired haemolytic anaemia, clonal in nature, due to somatic mutation… 
Review
1992
Review
1992
Primary, single, autosomal trisomies associated with haematological disorders. United Kingdom Cancer Cytogenetics Group (UKCCG).
Highly Cited
1991
Highly Cited
1991
Detection of trisomy 8 in hematological disorders by in situ hybridization.
An alphoid repetitive DNA (D8Z2) probe specific for the pericentromeric region of chromosome 8 was used to detect extra copies of… 
1991
1991
"Jumping" translocations involving band 3q13.3 in a case of acute monocytic leukemia.
1987
1987
Molecular characteristics of chronic myelogenous leukemia in blast crisis.
Review
1979
Review
1979
Complete and partial trisomy of different segments of chromosome 8: case reports and review
This report describes some of the clinical, chromosomal and radiological findings in three unrelated patients with trisomy 8… 
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