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Chlorthalidone

Known as: 3-Hydroxy-3-(4-chloro-3-sulfamylphenyl)phthalimidine, Oxodoline, 3-(4'-chloro-3'-Sulfamoylphenyl)-3-hydroxyphthalimidine 
A long acting thiazide-like diuretic of the sulfamoylbenzamide class that is devoid of the benzothiadiazine structure. Chlorthalidone directly… 
National Institutes of Health

Related topics

Related topics

30 relations

Broader (3)

Antihypertensive AgentsDiureticsbenzenesulfonamide
AnuriaChlorthalidone 25 MG Oral TabletChlorthalidone:MRat:24H:Urine:QnChlorthalidone:PrThr:Pt:Urine:Ord

Narrower (5)

Atenolol / ChlorthalidoneCombipresHygrotonTenoretic

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
A novel software tool for high throughput measurements of interconversion barriers: DCXplorer.
  • O. Trapp
  • Journal of chromatography. B, Analytical…
  • 2008
  • Corpus ID: 32627130
Review
2007
Review
2007
The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) Heart Failure Validation Study: diagnosis and prognosis.
Review
2002
Review
2002
Relationship of Antihypertensive Treatment Regimens and Change in Blood Pressure to Risk for Heart Failure in Hypertensive Patients Randomly Assigned to Doxazosin or Chlorthalidone: Further Analyses…
Context Previously published results of this randomized, double-blind trial showed that hypertensive patients treated with… 
2001
2001
Lewis base effects in the Baylis-Hillman reaction of imines with cyclohex-2-en-1-one and cyclopent-2-en-1-one.
In the Baylis-Hillman reaction of N-benzylidene-4-methyl-benzenesulfonamide with cyclohex-2-en-1-one or cyclopent-2-en-1-one, we… 
Highly Cited
2000
Highly Cited
2000
Human beta3-adrenergic receptor agonists containing 1,2,3-triazole-substituted benzenesulfonamides.
Compounds containing a 1,2,3-triazole-substituted benzenesulfonamide were prepared and found to be potent and selective human… 
Review
1996
Review
1996
Evidence for the efficacy of low-dose diuretic monotherapy.
Highly Cited
1993
Highly Cited
1993
Trial of antihypertensive intervention and management: greater efficacy with weight reduction than with a sodium-potassium intervention.
1989
1989
Mechanical, biochemical, and structural effects of vitamin D deficiency on the chick heart.
The effects of vitamin D deprivation on the chick heart were investigated from three aspects: cardiac contractility (+/- dP/dT… 
Highly Cited
1980
Highly Cited
1980
Trial of atenolol and chlorthalidone for hypertension in black South Africans.
Twenty-four black patients (Zulus) with hypertension participated in a double-blind, placebo-controlled cross-over trial of the… 
Highly Cited
1978
Highly Cited
1978
Dose response to chlorthalidone in patients with mild hypertension; Efficacy of a lower dose
A multicenter study of chlorthalidone was performed to determine the relative antihypertensive efficacy and side effects of doses… 
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