Chlorthalidone

Known as: 3-Hydroxy-3-(4-chloro-3-sulfamylphenyl)phthalimidine, Oxodoline, 3-(4'-chloro-3'-Sulfamoylphenyl)-3-hydroxyphthalimidine 
A long acting thiazide-like diuretic of the sulfamoylbenzamide class that is devoid of the benzothiadiazine structure. Chlorthalidone directly… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
There is significant controversy around whether chlorthalidone (CTD) is superior to hydrochlorothiazide (HCTZ) in hypertension… (More)
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Highly Cited
2006
Highly Cited
2006
Low-dose thiazide-type diuretics are recommended as initial therapy for most hypertensive patients. Chlorthalidone has… (More)
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Review
2004
Review
2004
Thiazide diuretics are one of the preferred pharmacologic treatments for hypertension. Hydrochlorothiazide and chlorthalidone… (More)
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Review
2004
Review
2004
Management of hypertension in the elderly should take into account, in particular, the possible negative impact of… (More)
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Highly Cited
2002
Highly Cited
2002
CONTEXT Antihypertensive therapy is well established to reduce hypertension-related morbidity and mortality, but the optimal… (More)
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Highly Cited
2002
Highly Cited
2002
CONTEXT Blood pressure control (<140/90 mm Hg) rates for hypertension fall far short of the US national goal of 50% or more… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND It is unclear whether the carotid intima-media thickness can be influenced by antihypertensive treatment and whether… (More)
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Highly Cited
1988
Highly Cited
1988
We examined the effectiveness of chlorthalidone or magnesium hydroxide in the prevention of recurrent calcium oxalate kidney… (More)
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Highly Cited
1980
Highly Cited
1980
Measurement of patient compliance is essential if management of low compliance is to be performed efficiently. We assessed the… (More)
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