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Chinese Shar-Pei

Known as: Shar-Pei 
The Chinese Shar-Pei is a heavily wrinkled dog with a large head, though dogs with smaller heads and tighter looking skins do occur in this breed… 
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes.
Highly Cited
2006
Highly Cited
2006
Biophysical and Structural Characterization of Polyethylenimine-Mediated siRNA Delivery in Vitro
PurposeThe goals of this study were as follows: 1) to evaluate the efficacy of different polyethylenimine (PEI) structures for… 
Highly Cited
2005
Highly Cited
2005
Exploring polyethylenimine‐mediated DNA transfection and the proton sponge hypothesis
The relatively high transfection efficiency of polyethylenimine (PEI) vectors has been hypothesized to be due to their ability to… 
Highly Cited
2004
Highly Cited
2004
Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer
Nonviral vectors based on polyethylenimine (PEI) usually contain an excess of PEI that is not complexed to DNA. Since unbound PEI… 
Highly Cited
2004
Highly Cited
2004
Insights into the mechanism of magnetofection using PEI‐based magnetofectins for gene transfer
Gene delivery by the use of magnetic forces, so‐called magnetofection, has been shown to enhance transfection efficiency of viral… 
Highly Cited
2002
Highly Cited
2002
Side‐effects of a systemic injection of linear polyethylenimine–DNA complexes
Systemic administration of linear polyethylenimine–DNA complexes (L‐PEI/DNA) results in transient expression of the transgene in… 
Highly Cited
2001
Highly Cited
2001
Chitosan as a nonviral gene delivery system. Structure–property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo
Chitosan is a natural cationic linear polymer that has recently emerged as an alternative nonviral gene delivery system. We have… 
Highly Cited
2000
Highly Cited
2000
Systemic linear polyethylenimine (L‐PEI)‐mediated gene delivery in the mouse
Several nonviral vectors including linear polyethylenimine(L‐PEI) confer a pronounced lung tropism to plasmid DNA when injected… 
Highly Cited
1999
Highly Cited
1999
Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery.
Poly(ethylenimine) (PEI) is one of a number of polycations that has been used successfully to transfer genes into living cells… 
Highly Cited
1998
Highly Cited
1998
Algorithmic Analysis of Nonlinear Hybrid Systems
We present two methods for translating nonlinear hybrid systems into linear hybrid automata. Properties of the nonlinear systems… 
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