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Chimeric Monoclonal Antibody B72.3

Known as: Chimeric B72.3 
A synthetic chimeric molecule in which a mouse monoclonal antibody variable region directed against the tumor-associated glycoprotein 72 (TAG-72) is… 
National Institutes of Health

Related topics

Related topics

1 relation
antigen binding

Papers overview

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1999
1999
Light-chain framework region residue Tyr71 of chimeric B72.3 antibody plays an important role in influencing the TAG72 antigen binding.
The crystallographic study of chimeric B72.3 antibody illustrated that there are three FR side-chain interactions with either CDR… 
1991
1991
Comparative biodistributions of Y-90 and In-111-macrocycle chimeric b72.3 conjugates in a human colon carcinoma xenograft model.
1990
1990
A preliminary investigation of the hydrodynamic properties of two novel monoclonal antibodies.
B72.3 is a murine monoclonal antibody which reacts with a range o f ovarian, breast and colon carcinomas. Its immunoscintigraphic… 
1990
1990
Rapid clearance of aglycosyl recombinant chimeric B72.3 (4) antibody in athymic mice bearing human colorectal xenografts
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