Chilblains

Known as: Chilblains [Disease/Finding], Idiopathic Perniosis, Perniosis 
A rare condition characterized by skin inflammation, blister formation, swelling and ulcerations in the extremities. It occurs in persons exposed to… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Detection of nucleic acids and induction of type I interferons (IFNs) are principal elements of antiviral defense but can cause… (More)
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Highly Cited
2007
Highly Cited
2007
TREX1 constitutes the major 3'-->5' DNA exonuclease activity measured in mammalian cells. Recently, biallelic mutations in TREX1… (More)
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Highly Cited
2007
Highly Cited
2007
TREX1 acts in concert with the SET complex in granzyme A–mediated apoptosis, and mutations in TREX1 cause Aicardi-Goutières… (More)
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Review
2007
Review
2007
Sarcoidosis is a multisystem disease with cutaneous lesions present in 20%-35% of patients. Given the wide variability of… (More)
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2003
2003
In our study, we retrospectively evaluated the clinical features of patients diagnosed as sarcoidosis at our center within the… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND AND AIM OF WORK Tumor necrosis factor-alpha (TNF-alpha) appears to be an important cytokine in the inflammation of… (More)
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2001
2001
BACKGROUND The histopathologic diagnosis of chilblains is controversial and the histologic changes are often considered… (More)
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Review
1997
Review
1997
Sarcoidosis is an antigen-mediated disease defined by granuloma formation in different organs. It involves mainly the mediastinal… (More)
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1990
1990
Unfamiliarity of physicians with chilblains (perniosis) gives rise to unnecessary hospital admissions with expensive laboratory… (More)
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Highly Cited
1983
Highly Cited
1983
A computerised, retrospective study of 818 patients with sarcoidosis was analysed to study the prognosis of each individual… (More)
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