Chief cell

Known as: Chief Cells 
Epithelial cells that line the basal half of the gastric glands. They synthesize and secrete pepsinogen, a precursor of the enzyme pepsin. (MeSH)
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
Proliferation of the self-renewing epithelium of the gastric corpus occurs almost exclusively in the isthmus of the glands, from… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND & AIMS Gastric cancer evolves in the setting of a pathologic mucosal milieu characterized by both loss of acid… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND & AIMS Loss of gastric parietal cells is a critical precursor to gastric metaplasia and neoplasia. However, the origin… (More)
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Review
2001
Review
2001
The cloning of a G protein-coupled extracellular Ca(2+) (Ca(o)(2+))-sensing receptor (CaR) has elucidated the molecular basis for… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND: Leptin plays an important role in the control of food intake and body weight homeostasis. In humans, leptin is… (More)
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Highly Cited
1996
Highly Cited
1996
Most parathyroid adenomas and some pathological parathyroid glands from patients with primary parathyroid hyperplasia or severe… (More)
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Highly Cited
1994
Highly Cited
1994
PHYSIOLOGISTS have long pondered the riddle of why the stomach is itself not digested by the very juice it secretes. One… (More)
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Highly Cited
1976
Highly Cited
1976
To define the histology of the columnarlined esophagus, we obtained esophageal biopsies from various levels with manometric… (More)
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Highly Cited
1976
Highly Cited
1976
The area occupied by parenchymal cells, in sections comprising the entire half of the surface of the carotid body, is… (More)
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Highly Cited
1963
Highly Cited
1963
A description of the cytology of the gastric mucosa is presented based upon an electron microscopic investigation of the bat… (More)
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