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Chief cell

Known as: Chief Cells 
Epithelial cells that line the basal half of the gastric glands. They synthesize and secrete pepsinogen, a precursor of the enzyme pepsin. (MeSH)
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
The daily renewal of the corpus epithelium is fuelled by adult stem cells residing within tubular glands, but the identity of… Expand
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Highly Cited
2013
Highly Cited
2013
Proliferation of the self-renewing epithelium of the gastric corpus occurs almost exclusively in the isthmus of the glands, from… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND & AIMS Gastric cancer evolves in the setting of a pathologic mucosal milieu characterized by both loss of acid… Expand
Highly Cited
2010
Highly Cited
2010
Only a few cases of gastric adenocarcinoma of fundic gland type have been reported. Gastric adenocarcinoma with chief cell… Expand
Review
2005
Review
2005
Secretion of bicarbonate into the adherent layer of mucus gel creates a pH gradient with a near-neutral pH at the epithelial… Expand
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Review
2001
Review
2001
The cloning of a G protein-coupled extracellular Ca(2+) (Ca(o)(2+))-sensing receptor (CaR) has elucidated the molecular basis for… Expand
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Highly Cited
1996
Highly Cited
1996
Most parathyroid adenomas and some pathological parathyroid glands from patients with primary parathyroid hyperplasia or severe… Expand
Highly Cited
1976
Highly Cited
1976
To define the histology of the columnarlined esophagus, we obtained esophageal biopsies from various levels with manometric… Expand
Highly Cited
1963
Highly Cited
1963
A description of the cytology of the gastric mucosa is presented based upon an electron microscopic investigation of the bat… Expand
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Highly Cited
1957
Highly Cited
1957
1. By the use of tryptamine as substrate in the presence of tetrazolium salts in a solution buffered to pH 7.6 histochemical… Expand
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