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Chemistry, Pharmaceutical

Known as: Pharmaceutical Chemistry, Medicinal Chemistry, Chemistry, Medicinal 
A chemistry-based discipline, also involving aspects of biological, medical and pharmaceutical sciences. It is concerned with the invention… 
National Institutes of Health

Related topics

Related topics

6 relations
BiopharmaceuticsDrug CompoundingEducational aspectsTechnology, Pharmaceutical

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
An Unprecedented Revolution in Medicinal Chemistry Driven by the Progress of Biological Science.
The eternal or ultimate goal of medicinal chemistry is to find most effective ways to treat various diseases and extend human… 
Highly Cited
2013
Highly Cited
2013
Catalytic asymmetric Michael addition/cyclization of isothiocyanato oxindoles: highly efficient and versatile approach for the synthesis of 3,2'-pyrrolidinyl mono- and bi-spirooxindole frameworks.
The spirooxindole core is a privileged heterocyclic ring system featured in a large number of natural or synthetic compounds with… 
Highly Cited
2013
Highly Cited
2013
Pd(II)-catalyzed ortho-trifluoromethylation of benzylamines.
The Pd(II)-catalyzed ortho-C-H trifluoromethylation of benzylamines has been achieved utilizing an electrophilic CF3 reagent… 
Review
2012
Review
2012
Tandem photoaffinity labeling-bioorthogonal conjugation in medicinal chemistry.
Highly Cited
2009
Highly Cited
2009
Copper as a powerful catalyst in the direct alkynylation of azoles.
The widespread use of heteroarenes in medicinal chemistry and in materials science has driven the development of a plethora of… 
Review
2004
Review
2004
Emerging classes of protein-protein interaction inhibitors and new tools for their development.
Highly Cited
2004
Highly Cited
2004
The merger of natural product synthesis and medicinal chemistry: on the chemistry and chemical biology of epothilones.
Based on epothilones as powerful natural product leads several promising new anticancer agents have emerged through concerted… 
Highly Cited
2001
Highly Cited
2001
Dimerization of G-protein-coupled receptors.
The evolutionary trace (ET) method, a data mining approach for determining significant levels of amino acid conservation, has… 
Highly Cited
2001
Highly Cited
2001
Solid-phase syntheses of beta-turn analogues to mimic or disrupt protein-protein interactions.
Protein-protein interactions are difficult targets in medicinal chemistry, but they will become increasingly important as data… 
Review
1993
Review
1993
Concepts and progress in the development of peptide mimetics.
Medicinal chemistry research has been dramatically transformed by biotechnology. Previously, synthetic chemistry and natural… 
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