Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Chemistry, Pharmaceutical

Known as: Pharmaceutical Chemistry, Medicinal Chemistry, Chemistry, Medicinal 
A chemistry-based discipline, also involving aspects of biological, medical and pharmaceutical sciences. It is concerned with the invention… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
To be effective as a drug, a potent molecule must reach its target in the body in sufficient concentration, and stay there in a… Expand
Highly Cited
2011
Highly Cited
2011
  • N. Meanwell
  • Journal of medicinal chemistry
  • 2011
  • Corpus ID: 26355203
The concept of isosterism between relatively simple chemical entities was originally contemplated by James Moir in 1909, a notion… Expand
  • figure 1
  • table 1
  • table 2
  • table 2.18
  • figure 2
Review
2010
Review
2010
Copper-catalyzed azide-alkyne cycloaddition (CuAAC) is a widely utilized, reliable, and straightforward way for making covalent… Expand
Highly Cited
2009
Highly Cited
2009
The medicinal chemistry community has become increasingly aware of the value of tracking calculated physical properties such as… Expand
  • figure 2
  • figure 1
  • figure 3
  • figure 5
  • figure 4
Review
2008
Review
2008
It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role… Expand
Review
2007
Review
2007
The application of guidelines linked to the concept of drug-likeness, such as the 'rule of five', has gained wide acceptance as… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Review
2003
Review
2003
Intermolecular interactions involving aromatic rings are key processes in both chemical and biological recognition. Their… Expand
Review
2003
Review
2003
Privileged substructures are of potentially great importance in medicinal chemistry. These scaffolds are characterized by their… Expand
Review
2001
Review
2001
Experimental and computational approaches to estimate solubility and permeability in discovery and development settings are… Expand
  • table I
  • table 3
Highly Cited
1991