Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 205,564,898 papers from all fields of science
Search
Sign In
Create Free Account
Checkpoint Kinase Inhibitor AZD7762
A synthetic small molecule inhibitor of checkpoint kinases (Chks) with potential chemosensitizing activity. AZD7762 binds to and inhibits Chks, which…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
1 relation
AZD 7762
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Redirecting extracellular proteases to molecularly guide radiosensitizing drugs to tumors.
Dina V. Hingorani
,
J. Crisp
,
+12 authors
S. Advani
Biomaterials
2020
Corpus ID: 215818821
2019
2019
Checkpoint kinase inhibitor AZD7762 enhance cisplatin-induced apoptosis in osteosarcoma cells
Jian Zhu
,
Hanhui Zou
,
+5 authors
Hui-min Tao
Cancer Cell International
2019
Corpus ID: 198932361
BackgroundAZD7762 is a checkpoint kinase 1 (Chk 1) inhibitor, which has been reported to sensitize many tumor cells to DNA damage…
Expand
2018
2018
Enhancing Abiraterone Acetate Efficacy in Androgen Receptor–positive Triple-negative Breast Cancer: Chk1 as a Potential Target
T. Grellety
,
C. Callens
,
+8 authors
B. Cardinaud
Clinical Cancer Research
2018
Corpus ID: 53026142
Purpose: Our aim was to identify predictive factors of abiraterone acetate efficacy and putative new druggable targets in…
Expand
2017
2017
Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine
M. Isono
,
M. Hoffmann
,
+5 authors
W. Schulz
Journal of experimental & clinical cancer…
2017
Corpus ID: 4457736
BackgroundMore effective chemotherapies are urgently needed for bladder cancer, a major cause of morbidity and mortality…
Expand
2014
2014
Checkpoint Kinase Inhibitor AZD7762 Overcomes Cisplatin Resistance in Clear Cell Carcinoma of the Ovary
H. Itamochi
,
M. Nishimura
,
+9 authors
T. Harada
International Journal of Gynecologic Cancer
2014
Corpus ID: 457304
Objective Checkpoint kinase (Chk) inhibitors are thought to increase the cytotoxic effects of DNA-damaging agents and are…
Expand
Highly Cited
2012
Highly Cited
2012
The Checkpoint Kinase Inhibitor AZD7762 Potentiates Chemotherapy-Induced Apoptosis of p53-Mutated Multiple Myeloma Cells
H. Landau
,
S. McNeely
,
+6 authors
G. Schwartz
Molecular Cancer Therapeutics
2012
Corpus ID: 16274400
DNA cross-linking agents are frequently used in the treatment of multiple myeloma–generating lesions, which activate checkpoint…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
,
Terms of Service
, and
Dataset License
ACCEPT & CONTINUE