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Checkpoint Kinase Inhibitor AZD7762

A synthetic small molecule inhibitor of checkpoint kinases (Chks) with potential chemosensitizing activity. AZD7762 binds to and inhibits Chks, which… 
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
DNA cross-linking agents are frequently used in the treatment of multiple myeloma–generating lesions, which activate checkpoint…