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Cephacetrile
Known as:
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-7-((cyanoacetyl)amino)-8-oxo-, monosodium salt, (6R-trans)-
, Cephacetrile [Chemical/Ingredient]
, Cefacetrilo
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A broad-spectrum first-generation cephalosporin with antibacterial activity. Cephacetrile binds to and inactivates penicillin-binding proteins (PBPs…
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National Institutes of Health
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Related topics
Related topics
11 relations
Broader (1)
Anti-Bacterial Agents
Narrower (3)
Celospor
Cephacetrile Sodium
Flunicef
In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Comparative evaluation of cephacetrile in experimentally induced bovine mastitis.
J. Schluep
,
A. Rosselet
,
H. Heim
Zentralblatt fur Veterinarmedizin. Reihe B…
2010
Corpus ID: 38057752
Summary This work describes the development of a reproducible mastitis model in the milking cow. The model serves to compare…
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Highly Cited
1985
Highly Cited
1985
Studies on the promoting effects of carboxylic acid derivatives on the rectal absorption of beta-lactam antibiotics in rats.
K. Nishimura
,
Y. Nozaki
,
+4 authors
K. Kitao
Chemical and pharmaceutical bulletin
1985
Corpus ID: 39106498
The promoting effects of sodium salts of N-acyl-L-phenylalanines, p-substituted benzoic acids, saturated straight-chain fatty…
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Highly Cited
1979
Highly Cited
1979
Effects of subminimal inhibitory concentrations of antibiotics on adhesiveness of Escherichia coli in vitro.
K. Vosbeck
,
H. Handschin
,
E. B. Menge
,
O. Zak
Reviews of Infectious Diseases
1979
Corpus ID: 13637699
The adhesion of radiolabeled Escherichia coli (strain SS142) to monolayers of Intestine 407, a human epithelioid tissue culture…
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1976
1976
Metabolic fate of cephacetrile after parenteral administration in rats and rabbits.
Y. Nakai
,
Y. Kanai
,
T. Fugono
,
S. Tanayama
Journal of antibiotics (Tokyo. )
1976
Corpus ID: 20179236
1. The metabolic fate of 14C-cephacetrile was studied in rats and rabbits. The plasma level of intravenously injected…
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Highly Cited
1975
Highly Cited
1975
Knee joint infections with Staphylococcus aureus and Micrococcus species.
D. Schurman
,
B. Johnson
,
H. Amstutz*
Journal of Bone and Joint Surgery. American…
1975
Corpus ID: 9747268
In rabbit knees 600 Staphylococcus aureus organisms produced progressive infection in 50 per cent of the knees injected, whereas…
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1974
1974
Availability of three antibiotics after intramuscular injection into thigh and buttock.
D. Reeves
,
M. Bywater
,
R. Wise
,
V. Whitmarsh
The Lancet
1974
Corpus ID: 37898602
1973
1973
Biliary Excretion of a New Semisynthetic Cephalosporin, Cephacetrile
J. Brogard
,
P. Haegelé
,
M. Dorner
,
J. Lavillaureix
Antimicrobial Agents and Chemotherapy
1973
Corpus ID: 19918425
The biliary excretion of a new derivative of cephalosporin, cephacetrile (CIBA 36 278 Ba), was studied (i) in the isolated…
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1973
1973
Cephacetrile: Clinical Evaluation in 27 Patients
G. Hodges
,
J. Scholand
,
R. Perkins
Antimicrobial Agents and Chemotherapy
1973
Corpus ID: 45724447
Cephacetrile, a new derivative of 7-aminocephalosporanic acid, was evaluated in 27 patients. Soft tissue infections due primarily…
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1972
1972
Effect of renal failure and hemodialysis on cephacetrile pharmacoki netics
A. Nissenson
,
N. Levin
,
R. H. Parker
Clinical pharmacology and therapy
1972
Corpus ID: 40262070
Cephacetrile, a new injectable cephalosporin antibiotic that is allegedly not nephrotoxic, was evaluated in 15 subjects with…
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1972
1972
In vitro evaluation of cephacetrile, a new cephalosporin antibiotic.
H. Neu
,
E. Winshell
Journal of antibiotics (Tokyo. )
1972
Corpus ID: 42153807
Cephacetrile, 7-cyanacetamido-cephalosporanic acid, is a new cephalosporin active against many gram-positive and gram-negative…
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