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Cephacetrile

Known as: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-7-((cyanoacetyl)amino)-8-oxo-, monosodium salt, (6R-trans)-, Cephacetrile [Chemical/Ingredient], Cefacetrilo 
A broad-spectrum first-generation cephalosporin with antibacterial activity. Cephacetrile binds to and inactivates penicillin-binding proteins (PBPs… 
National Institutes of Health

Papers overview

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2013
2013
The Charm maximum residue limit β-lactam and tetracycline test (Charm MRL BLTET; Charm Sciences Inc., Lawrence, MA) is an… 
2010
2010
Summary This work describes the development of a reproducible mastitis model in the milking cow. The model serves to compare… 
Highly Cited
1982
Highly Cited
1982
Pyridine-2-azo-p-dimethylanaline cephalosporin (PADAC), a chromogenic reagent which is purple and changes to yellow upon cleavage… 
Highly Cited
1979
Highly Cited
1979
The adhesion of radiolabeled Escherichia coli (strain SS142) to monolayers of Intestine 407, a human epithelioid tissue culture… 
Highly Cited
1978
Highly Cited
1978
A new apparatus is described which serves to investigate the in vitro antibacterial activity of antibiotics as a function of… 
1978
1978
Six cephalosporin antibiotics (cefamandole, cefazolin, cephacetrile, cephalothin, cephaloridine, and cephradine) and two… 
1976
1976
1. The metabolic fate of 14C-cephacetrile was studied in rats and rabbits. The plasma level of intravenously injected… 
1973
1973
Cephacetrile, a new derivative of 7-aminocephalosporanic acid, was evaluated in 27 patients. Soft tissue infections due primarily… 
1973
1973
The biliary excretion of a new derivative of cephalosporin, cephacetrile (CIBA 36 278 Ba), was studied (i) in the isolated… 
1972
1972
Cephacetrile, a new injectable cephalosporin antibiotic that is allegedly not nephrotoxic, was evaluated in 15 subjects with…