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Cephacetrile

Known as: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-7-((cyanoacetyl)amino)-8-oxo-, monosodium salt, (6R-trans)-, Cephacetrile [Chemical/Ingredient], Cefacetrilo 
A broad-spectrum first-generation cephalosporin with antibacterial activity. Cephacetrile binds to and inactivates penicillin-binding proteins (PBPs… Expand
National Institutes of Health

Papers overview

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2017
2017
A method was developed for the confirmatory and quantitative analysis of 30 β-lactam antibiotic residues in bovine muscle. The… Expand
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2013
2013
A simple, sensitive and reliable analytical method was developed for the simultaneous determination of 10 cephalosporins and… Expand
Highly Cited
1982
Highly Cited
1982
Pseudomonas aeruginosa is usually resistant to a wide variety of antibacterial agents, and it has been inferred, on the basis of… Expand
Highly Cited
1982
Highly Cited
1982
Pyridine-2-azo-p-dimethylanaline cephalosporin (PADAC), a chromogenic reagent which is purple and changes to yellow upon cleavage… Expand
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Highly Cited
1979
Highly Cited
1979
The adhesion of radiolabeled Escherichia coli (strain SS142) to monolayers of Intestine 407, a human epithelioid tissue culture… Expand
Highly Cited
1978
Highly Cited
1978
A new apparatus is described which serves to investigate the in vitro antibacterial activity of antibiotics as a function of… Expand
1978
1978
Six cephalosporin antibiotics (cefamandole, cefazolin, cephacetrile, cephalothin, cephaloridine, and cephradine) and two… Expand
Highly Cited
1977
Highly Cited
1977
Cephaloglycin, cephalothin, cephaloridine, cefoxitin, and cephacetrile are cephalosporin antibiotics that react with alkaline… Expand
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1976
1976
1. The metabolic fate of 14C-cephacetrile was studied in rats and rabbits. The plasma level of intravenously injected… Expand
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1972
1972
Cephacetrile, a new injectable cephalosporin antibiotic that is allegedly not nephrotoxic, was evaluated in 15 subjects with… Expand