Cephacetrile

Known as: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-7-((cyanoacetyl)amino)-8-oxo-, monosodium salt, (6R-trans)-, Cephacetrile [Chemical/Ingredient], Cefacetrilo 
A broad-spectrum first-generation cephalosporin with antibacterial activity. Cephacetrile binds to and inactivates penicillin-binding proteins (PBPs… (More)
National Institutes of Health

Papers overview

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2013
2013
The Charm maximum residue limit β-lactam and tetracycline test (Charm MRL BLTET; Charm Sciences Inc., Lawrence, MA) is an… (More)
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2013
2013
A simple, sensitive and reliable analytical method was developed for the simultaneous determination of 10 cephalosporins and… (More)
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1982
1982
Pyridine-2-azo-p-dimethylanaline cephalosporin (PADAC), a chromogenic reagent which is purple and changes to yellow upon cleavage… (More)
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1979
1979
The pharmacokinetics of cephacetrile were studied after its administration as a single i.v. bolus injection of 15 mg/kg body… (More)
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Highly Cited
1978
Highly Cited
1978
A new apparatus is described which serves to investigate the in vitro antibacterial activity of antibiotics as a function of… (More)
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1978
1978
The pharmacokinetics of cephacetrile, administered as a single i. v. injection of 15 mg/kg, have been determined in 8 patients… (More)
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1977
1977
Cephaloglycin, cephalothin, cephaloridine, cefoxitin, and cephacetrile are cephalosporin antibiotics that react with alkaline… (More)
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1977
1977
The serum half-life of cephacetrile and its penetration from the serum into the cerebrospinal fluid (CSF) was determined in 33… (More)
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1973
1973
The biliary excretion of a new derivative of cephalosporin, cephacetrile (CIBA 36 278 Ba), was studied (i) in the isolated… (More)
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1973
1973
Cephacetrile, a new derivative of 7-aminocephalosporanic acid, was evaluated in 27 patients. Soft tissue infections due primarily… (More)
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