Skip to search formSkip to main contentSkip to account menu

Cellular Assay

In vitro experiments conducted with intact, living cells.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Design and synthesis of alkyl substituted pyridino[2,3-D]pyrimidine compounds as PI3Kα/mTOR dual inhibitors with improved pharmacokinetic properties and potent in vivo antitumor activity.
2014
2014
Capillary electrophoresis-based assessment of nanobody affinity and purity.
2010
2010
BacMam-Enabled LanthaScreen® Cellular Assays for PI3K/Akt Pathway Compound Profiling in Disease-Relevant Cell Backgrounds
The authors recently reported the development and application of multiple LanthaScreen® cellular assays to interrogate specific… 
2006
2006
A cellular assay for measuring the modulation of glucose production in H4IIE cells.
Type II diabetes and its associated complications are a major health concern of the developed world. One of the hallmarks of… 
Highly Cited
2005
Highly Cited
2005
Methyl scanning: total synthesis of demethylasterriquinone B1 and derivatives for identification of sites of interaction with and isolation of its receptor(s).
The principle of methyl scanning is proposed for determination of the sites of interaction between biologically active small… 
Highly Cited
2004
Highly Cited
2004
Synthesis of Hydroxy Derivatives of Highly Potent Non-steroidal CYP 17 Inhibitors as Potential Metabolites and Evaluation of their Activity by a Non Cellular Assay using Recombinant Human Enzyme
Inhibition of CYP 17 is a promising strategy for the treatment of prostate cancer. Recently two non-steroidal compounds with high… 
2002
2002
A novel N-methyl-D-aspartate receptor open channel blocker with in vivo neuroprotectant activity.
Excitotoxicity has been implicated in the etiology of ischemic stroke, chronic neurodegenerative disorders, and very recently, in… 
1993
1993
Establishment of a cellular assay system for G protein-linked receptors: coupling of human NK2 and 5-HT2 receptors to phospholipase C activates a luciferase reporter gene.
A functional cellular assay system was developed for the detection of substances modulating the activity of G protein-coupled… 
1991
1991
Production of multimeric forms of CD4 through a sugar-based cross-linking strategy.
1975
1975
MODIFICATION OF THE RAT ALLOIMMUNE RESPONSE BY ENHANCING ANTIBODIES AND THE ROLE OF BLOCKING FACTORS IN THE SURVIVAL OF RENAL GRAFTS
Correlation of morphological and immunological events occurring in control and passively enhanced rat renal allograft recipients… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)