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Cefonicid

Known as: (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, Cefonicido, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((hydroxyphenylacetyl)amino)-8-oxo-3-(((1-(sulfomethyl)-1H-tetrazol-5-yl)thio)methyl)-, (6R-(6alpha,7beta(R*)))- 
A second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefonicid binds to penicillin-binding proteins… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (1)

Anti-Bacterial Agents
Cefonicid MonosodiumIn Bloodagonistsanalogs & derivatives

Narrower (2)

MonocidSK&F-75073

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1986
1986
Antistaphylococcal activity of ceforanide and cefonicid in the presence of human serum
Tests with 52 strains of Staphylococcus aureus compared ceforanide and cefonicid. Addition of 50% human serum to the test system… 
1985
1985
Cross-over study of the pharmacokinetics of cefonicid administered intravenously or intramuscularly to healthy adult humans
SummaryThe pharmacokinetics of cefonicid were investigated in eight healthy adults. A one-gram dose was administered either… 
1984
1984
Cefonicid in a once-daily regimen for treatment of osteomyelitis in an ambulatory setting.
Fifteen patients with bone joint infections were treated with 1.0 g of cefonicid administered intravenously or intramuscularly… 
Review
1984
Review
1984
Review of cefonicid, a long-acting cephalosporin.
The in vitro activity, pharmacokinetics, adverse effects, and clinical efficacy of cefonicid are reviewed. Also discussed are… 
1984
1984
Penetration of cefonicid into human breast milk and various body fluids and tissues.
A new cephalosporin, cefonicid (1 g), was given intramuscularly to 49 patients 1 hr before they were to undergo surgery and to 10… 
1984
1984
Tissue penetration and half-life of cefonicid.
The pharmacokinetics of cefonicid in the serum and tissues of patients undergoing open heart surgery, vaginal hysterectomy, and… 
1984
1984
Pharmacokinetic disposition of cefonicid in patients with renal failure and receiving hemodialysis.
Cefonicid is a new cephalosporin with a spectrum of activity similar to that of cefamandole. The pharmacokinetic disposition of… 
1984
1984
Prophylactic antibiotics for elective colorectal surgery or operation for obstruction of the small bowel: a comparison of cefonicid and cefoxitin.
Elective colorectal surgery carries a rate of septic complications of up to 35% in patients not receiving prophylaxis. This can… 
1983
1983
Evaluation of the cefonicid disk test criteria, including disk quality control guidelines
Cefonicid (SKF 75073) is a second-generation cephalosporin which has a spectrum of antimicrobial activity similar to that of… 
1983
1983
Single-dose cefonicid therapy for urinary tract infections
The efficacy of single-dose therapy with cefonicid (1 g intramuscularly) and multidose therapy with amoxicillin (500 mg orally… 
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