Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Cefonicid

Known as: (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, Cefonicido, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((hydroxyphenylacetyl)amino)-8-oxo-3-(((1-(sulfomethyl)-1H-tetrazol-5-yl)thio)methyl)-, (6R-(6alpha,7beta(R*)))- 
A second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefonicid binds to penicillin-binding proteins… Expand
National Institutes of Health

Related topics

Related topics

11 relations

Broader (1)

Anti-Bacterial Agents
Cefonicid MonosodiumIn Bloodagonistsanalogs & derivatives
Expand

Narrower (2)

MonocidSK&F-75073

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Immediate allergic reactions to cephalosporins: evaluation of cross-reactivity with a panel of penicillins and cephalosporins.
BACKGROUND Allergy to cephalosporins has mainly been evaluated in the context of patients with confirmed penicillin allergy. The… Expand
  • figure 1
  • figure 2
  • table I
  • table II
  • figure 3
Is this relevant?
1993
1993
Randomized trial comparing ceftriaxone with cefonicid for treatment of spontaneous bacterial peritonitis in cirrhotic patients.
We compared cefonicid (2 g every 12 h) and ceftriaxone (2 g every 24 h) for their efficacy and safety in treating spontaneous… Expand
Is this relevant?
1992
1992
Decreased susceptibility of penicillin-resistant pneumococci to twenty-four beta-lactam antibiotics.
The in-vitro activity of 24 beta-lactam antibiotics was compared using three groups of pneumococci and an agar dilution method… Expand
Is this relevant?
1991
1991
Prophylaxis against infection. Single-dose cefonicid compared with multiple-dose cefamandole.
A total of 1489 patients were included in a prospective, randomized study that compared the efficacy of a single dose of… Expand
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Perioperative antibiotic prophylaxis for herniorrhaphy and breast surgery.
We assessed the efficacy of perioperative antibiotic prophylaxis for surgery in a randomized, double-blind trial of 1218 patients… Expand
Is this relevant?
1984
1984
Failure of a once-daily regimen of cefonicid for treatment of endocarditis due to Staphylococcus aureus.
Cefonicid, a new long-acting cephalosporin, was evaluated for treatment of endocarditis due to Staphylococcus aureus. Four… Expand
Is this relevant?
1984
1984
Cefonicid in a once-daily regimen for treatment of osteomyelitis in an ambulatory setting.
Fifteen patients with bone joint infections were treated with 1.0 g of cefonicid administered intravenously or intramuscularly… Expand
Is this relevant?
1984
1984
A double-blind study comparing cefonicid with cefazolin as prophylaxis in patients undergoing total hip or knee replacement.
In a randomized double-blind design, cefonicid, an investigational cephalosporin, was compared with cefazolin as prophylaxis in… Expand
Is this relevant?
1984
1984
Comparative penetration of cefonicid and cefazolin into the atrial appendage and pericardial fluid of patients undergoing open-heart surgery.
The penetration of cefonicid and cefazolin into cardiac tissue was compared after a single 30-mg/kg dose in 30 patients… Expand
  • table 1
  • table 2
Is this relevant?
1982
1982
Pharmacokinetics of cefonicid, a new broad-spectrum cephalosporin.
This study determined the pharmacokinetic disposition of cefonicid. A single dose of 7.5 mg/kg of body weight was administered to… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE