Cefonicid

Known as: (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, Cefonicido, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((hydroxyphenylacetyl)amino)-8-oxo-3-(((1-(sulfomethyl)-1H-tetrazol-5-yl)thio)methyl)-, (6R-(6alpha,7beta(R*)))- 
A second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefonicid binds to penicillin-binding proteins… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2017
010203019802017

Papers overview

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1994
1994
We report a case of delayed cutaneous reaction to intramuscular treatment with cefonicid, a second generation cephalosporin. An… (More)
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1993
1993
We compared cefonicid (2 g every 12 h) and ceftriaxone (2 g every 24 h) for their efficacy and safety in treating spontaneous… (More)
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1991
1991
A total of 1489 patients were included in a prospective, randomized study that compared the efficacy of a single dose of… (More)
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Highly Cited
1990
Highly Cited
1990
We assessed the efficacy of perioperative antibiotic prophylaxis for surgery in a randomized, double-blind trial of 1218 patients… (More)
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1984
1984
Cefonicid, a new long-acting cephalosporin, was evaluated for treatment of endocarditis due to Staphylococcus aureus. Four… (More)
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1984
1984
Cefonicid was found to be highly active in vitro against greater than 5,000 bacterial isolates. Its spectrum of activity was… (More)
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1984
1984
The pharmacokinetics of cefonicid in the serum and tissues of patients undergoing open heart surgery, vaginal hysterectomy, and… (More)
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1982
1982
Cefonicid (Smith Kline & French Laboratories; D-75073) is a new parenteral cephalosporin with a markedly long half-life, high… (More)
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1981
1981
Cefonicid kinetics were determined after intravenous and intramuscular injection and the renal handling of the drug was examined… (More)
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1981
1981
The stability of cefonicid (SK&F 75073) towards representatives of six major classes of beta-lactamases was determined using a… (More)
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