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Cefonicid

Known as: (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, Cefonicido, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((hydroxyphenylacetyl)amino)-8-oxo-3-(((1-(sulfomethyl)-1H-tetrazol-5-yl)thio)methyl)-, (6R-(6alpha,7beta(R*)))- 
A second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefonicid binds to penicillin-binding proteins… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (1)

Anti-Bacterial Agents
Cefonicid MonosodiumIn Bloodagonistsanalogs & derivatives

Narrower (2)

MonocidSK&F-75073

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
Antibiotic for cesarean section: the case for ‘true’ prophylaxis
1991
1991
Quality control limits for disk diffusion and broth microdilution susceptibility tests with Haemophilus test medium.
1988
1988
Effect of cephalosporins on bilirubin-albumin binding.
1987
1987
Effects of cefonicid and other cephalosporin antibiotics on male sexual development in rats
The purpose of this study was to determine whether cefonicid, a cephalosporin antibiotic with a modified N-methylthiotetrazole… 
1984
1984
Cefonicid in a once-daily regimen for treatment of osteomyelitis in an ambulatory setting.
Fifteen patients with bone joint infections were treated with 1.0 g of cefonicid administered intravenously or intramuscularly… 
1984
1984
A double-blind study comparing cefonicid with cefazolin as prophylaxis in patients undergoing total hip or knee replacement.
In a randomized double-blind design, cefonicid, an investigational cephalosporin, was compared with cefazolin as prophylaxis in… 
Review
1984
Review
1984
Review of cefonicid, a long-acting cephalosporin.
The in vitro activity, pharmacokinetics, adverse effects, and clinical efficacy of cefonicid are reviewed. Also discussed are… 
1983
1983
Evaluation of the cefonicid disk test criteria, including disk quality control guidelines
Cefonicid (SKF 75073) is a second-generation cephalosporin which has a spectrum of antimicrobial activity similar to that of… 
1982
1982
Pharmacokinetics of cefonicid, a new broad-spectrum cephalosporin
This study determined the pharmacokinetic disposition of cefonicid. A single dose of 7.5 mg/kg of body weight was administered to… 
1981
1981
Kinetics and renal handling of cefonicid
Cefonicid kinetics were determined after intravenous and intramuscular injection and the renal handling of the drug was examined… 
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