Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Cefonicid

Known as: (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, Cefonicido, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((hydroxyphenylacetyl)amino)-8-oxo-3-(((1-(sulfomethyl)-1H-tetrazol-5-yl)thio)methyl)-, (6R-(6alpha,7beta(R*)))- 
A second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefonicid binds to penicillin-binding proteins… Expand
National Institutes of Health

Related topics

Related topics

11 relations

Broader (1)

Anti-Bacterial Agents
Cefonicid MonosodiumIn Bloodagonistsanalogs & derivatives
Expand

Narrower (2)

MonocidSK&F-75073

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Immediate allergic reactions to cephalosporins: evaluation of cross-reactivity with a panel of penicillins and cephalosporins.
BACKGROUND Allergy to cephalosporins has mainly been evaluated in the context of patients with confirmed penicillin allergy. The… Expand
  • figure 1
  • figure 2
  • table I
  • table II
  • figure 3
Highly Cited
1996
Highly Cited
1996
Short‐term versus long‐term antimicrobial prophylaxis in oncologic head and neck surgery
Although antimicrobial prophylaxis is mandatory in major clean‐contaminated oncologic surgery of the head and neck, both the… Expand
Highly Cited
1995
Highly Cited
1995
Relationship between structure and convulsant properties of some beta-lactam antibiotics following intracerebroventricular microinjection in rats.
The epileptogenic activities of several beta-lactam antibiotics were compared following their intracerebroventricular… Expand
  • figure 1
  • figure 3
  • figure 2
  • figure 5
  • figure 4
Highly Cited
1993
Highly Cited
1993
Randomized trial comparing ceftriaxone with cefonicid for treatment of spontaneous bacterial peritonitis in cirrhotic patients.
We compared cefonicid (2 g every 12 h) and ceftriaxone (2 g every 24 h) for their efficacy and safety in treating spontaneous… Expand
  • table 1
  • table 2
  • figure 1
  • table 3
1991
1991
Prophylaxis against infection. Single-dose cefonicid compared with multiple-dose cefamandole.
A total of 1489 patients were included in a prospective, randomized study that compared the efficacy of a single dose of… Expand
Highly Cited
1990
Highly Cited
1990
Perioperative antibiotic prophylaxis for herniorrhaphy and breast surgery.
We assessed the efficacy of perioperative antibiotic prophylaxis for surgery in a randomized, double-blind trial of 1218 patients… Expand
Highly Cited
1984
Highly Cited
1984
Failure of a once-daily regimen of cefonicid for treatment of endocarditis due to Staphylococcus aureus.
Cefonicid, a new long-acting cephalosporin, was evaluated for treatment of endocarditis due to Staphylococcus aureus. Four… Expand
1984
1984
Cefonicid in a once-daily regimen for treatment of osteomyelitis in an ambulatory setting.
Fifteen patients with bone joint infections were treated with 1.0 g of cefonicid administered intravenously or intramuscularly… Expand
1982
1982
Pharmacokinetics of cefonicid, a new broad-spectrum cephalosporin.
This study determined the pharmacokinetic disposition of cefonicid. A single dose of 7.5 mg/kg of body weight was administered to… Expand
  • figure 1
  • table 1
  • table 2
1981
1981
Kinetics and renal handling of cefonicid
Cefonicid kinetics were determined after intravenous and intramuscular injection and the renal handling of the drug was examined… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE