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Cefonicid
Known as:
(6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
, Cefonicido
, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((hydroxyphenylacetyl)amino)-8-oxo-3-(((1-(sulfomethyl)-1H-tetrazol-5-yl)thio)methyl)-, (6R-(6alpha,7beta(R*)))-
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A second-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefonicid binds to penicillin-binding proteins…
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National Institutes of Health
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Related topics
Related topics
11 relations
Broader (1)
Anti-Bacterial Agents
Cefonicid Monosodium
In Blood
agonists
analogs & derivatives
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Narrower (2)
Monocid
SK&F-75073
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Immediate allergic reactions to cephalosporins: evaluation of cross-reactivity with a panel of penicillins and cephalosporins.
C. Antúnez
,
N. Blanca-López
,
+5 authors
M. Blanca
The Journal of allergy and clinical immunology
2006
Corpus ID: 16105631
Review
2002
Review
2002
Ceftriaxone: an update of its use in the management of community-acquired and nosocomial infections.
H. Lamb
,
D. Ormrod
,
L. Scott
,
D. Figgitt
Drugs
2002
Corpus ID: 195689673
UNLABELLED Ceftriaxone is a parenteral third-generation cephalosporin with a long elimination half-life which permits once-daily…
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1998
1998
Prospective, randomized, double-blind study of prophylactic antibiotics in axillary lymph node dissection.
R. Bold
,
P. Mansfield
,
+6 authors
M. Ross
American journal of surgery
1998
Corpus ID: 39758836
Highly Cited
1996
Highly Cited
1996
Short‐term versus long‐term antimicrobial prophylaxis in oncologic head and neck surgery
M. Righi
,
R. Manfredi
,
G. Farneti
,
E. Pasquini
,
V. Cenacchi
Head & neck
1996
Corpus ID: 42722575
Although antimicrobial prophylaxis is mandatory in major clean‐contaminated oncologic surgery of the head and neck, both the…
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Highly Cited
1993
Highly Cited
1993
Randomized trial comparing ceftriaxone with cefonicid for treatment of spontaneous bacterial peritonitis in cirrhotic patients
J. Gómez-Jiménez
,
E. Ribera
,
+4 authors
J. Martínez-Vázquez
Antimicrobial Agents and Chemotherapy
1993
Corpus ID: 23933385
We compared cefonicid (2 g every 12 h) and ceftriaxone (2 g every 24 h) for their efficacy and safety in treating spontaneous…
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Highly Cited
1990
Highly Cited
1990
Perioperative antibiotic prophylaxis for herniorrhaphy and breast surgery.
R. Platt
,
D. Zaleznik
,
+7 authors
K. Holbrook
The New England journal of medicine
1990
Corpus ID: 27197745
We assessed the efficacy of perioperative antibiotic prophylaxis for surgery in a randomized, double-blind trial of 1218 patients…
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Highly Cited
1990
Highly Cited
1990
Antibiotic prophylaxis: is there a difference?
S. Faro
,
M. Martens
,
H. Hammill
,
G. Riddle
,
G. Tortolero
American journal of obstetrics and gynecology
1990
Corpus ID: 21864245
Review
1984
Review
1984
Ceftriaxone. A review of its antibacterial activity, pharmacological properties and therapeutic use.
D. Richards
,
R. Heel
,
R. N. Brogden
,
T. Speight
,
G. Avery
Drugs
1984
Corpus ID: 195693002
Ceftriaxone is a new 'third generation' semisynthetic cephalosporin with a long half-life which has resulted in a recommended…
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Highly Cited
1984
Highly Cited
1984
Failure of a once-daily regimen of cefonicid for treatment of endocarditis due to Staphylococcus aureus.
H. Chambers
,
J. Mills
,
T. Drake
,
M. Sande
Reviews of infectious diseases
1984
Corpus ID: 38291382
Cefonicid, a new long-acting cephalosporin, was evaluated for treatment of endocarditis due to Staphylococcus aureus. Four…
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1982
1982
Pharmacokinetics of cefonicid, a new broad-spectrum cephalosporin
S. Barriere
,
G. J. Hatheway
,
J. Gambertoglio
,
E. Lin
,
J. Conte
Antimicrobial Agents and Chemotherapy
1982
Corpus ID: 38976051
This study determined the pharmacokinetic disposition of cefonicid. A single dose of 7.5 mg/kg of body weight was administered to…
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