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Cefatrizine

Known as: 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-8-oxo-3-((1H-1,2,3-triazol-4-ylthio)methyl)-, (6R-(6alpha,7beta(R*)))-, Cefatrizine [Chemical/Ingredient] 
A broad-spectrum, semisynthetic, first-generation cephalosporin with antibacterial activity. Cefatrizine binds to and inactivates penicillin-binding… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (1)

Anti-Bacterial Agents

Narrower (3)

BL-S 640S 640-PSK&F-60771
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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2000
2000
Pharmacokinetics and pharmacodynamics of oral cephalosporins as critical factors in choice of antibiotics.
1990
1990
Saturable rate of cefatrizine absorption after oral administration to humans
This study examined the absorption kinetics of cefatrizine, an amino-β-lactam antibiotic, after oral administration of a single… 
1990
1990
[Randomized study of cefatrizine versus cefaclor in conjunctivitis otitis syndrome].
The association conjunctivitis-otitis is highly suggestive of Haemophilus influenzae infection. This conjunctivitis otitis… 
1988
1988
Characterization of the Oral Absorption of β-Lactam Antibiotics. I. Cephalosporins: Determination of Intrinsic Membrane Absorption Parameters in the Rat Intestine In Situ
The oral absorption of five cephalosporin antibiotics, cefaclor, cefadroxil, cefatrizine, cephalexin, and cephradine, has been… 
1987
1987
Clinical pharmacokinetics of five oral cephalosporins in calves.
1983
1983
Human intravenous pharmacokinetics and absolute oral bioavailability of cefatrizine
Cefatrizine was administered intravenously and orally at dose levels of 250, 500, and 1,000 mg to normal male volunteers in a… 
1978
1978
Comparative absorption following the administration of a drug to rats by oral gavage and incorporation in the diet.
1976
1976
Cefatrizine (SK&F 60771), a New Oral Cephalosporin: Serum Levels and Urinary Recovery in Humans After Oral or Intramuscular Administration – Comparative Study with Cephalexin and Cefazolin
Cefatrizine (SK&F 60771), a new broad-spectrum cephalosporin, was administered in a 0.5-g dose either orally or intramuscularly… 
1976
1976
In Vitro and Clinical Studies of Cefatrizine, a New Semisynthetic Cephalosporin
Cefatrizine, a new oral semisynthetic cephalosporin, was evaluated in vitro and in the treatment of 18 patients with acute… 
1976
1976
The in vitro spectrum of the cephalosporins.
The cephalosporins may currently be classified according to their relative susceptibility to beta-lactamases. Cefoxitin… 
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