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Catenin Delta-1

Known as: p120 Catenin, Cadherin-Associated Src Substrate, catenin p120ctn protein 
Catenin delta-1 (968 aa, ~108 kDa) is encoded by the human CTNND1 gene. This protein plays a role in receptor-mediated signaling.
National Institutes of Health

Related topics

Related topics

8 relations
Armadillo RepeatCTNND1 geneCTNND1 wt AlleleHomo sapiens

Broader (1)

delta catenins

Papers overview

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Highly Cited
2007
Highly Cited
2007
E-cadherin homophilic ligation inhibits cell growth and epidermal growth factor receptor signaling independently of other cell interactions.
E-cadherin function leads to the density-dependent contact inhibition of cell growth. Because cadherins control the overall state… 
Review
2006
Review
2006
Catenins: keeping cells from getting their signals crossed.
Highly Cited
2003
Highly Cited
2003
p120 catenin associates with kinesin and facilitates the transport of cadherin–catenin complexes to intercellular junctions
p120 catenin (p120) is a component of adherens junctions and has been implicated in regulating cadherin-based cell adhesion as… 
Highly Cited
2002
Highly Cited
2002
A novel role for p120 catenin in E-cadherin function
Îndirect evidence suggests that p120-catenin (p120) can both positively and negatively affect cadherin adhesiveness. Here we show… 
Highly Cited
2002
Highly Cited
2002
The p120ctn-binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG dinucleotides
The p120(ctn)-binding partner Kaiso is a new member of the POZ-zinc finger family of transcription factors implicated in… 
Highly Cited
2001
Highly Cited
2001
p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell-cell contact formation and regulation of cell locomotion.
The molecular basis for contact inhibition of cell locomotion is still largely unknown. Cadherins, the major receptors mediating… 
Review
2001
Review
2001
Regulation of Rho GTPases by p120-catenin.
Highly Cited
2001
Highly Cited
2001
Modulation of mouse neural crest cell motility by N-cadherin and connexin 43 gap junctions
Connexin 43 (Cx43α1) gap junction has been shown to have an essential role in mediating functional coupling of neural crest cells… 
Highly Cited
1998
Highly Cited
1998
The Juxtamembrane Region of the Cadherin Cytoplasmic Tail Supports Lateral Clustering, Adhesive Strengthening, and Interaction with p120ctn
Cadherin cell–cell adhesion molecules form membrane-spanning molecular complexes that couple homophilic binding by the cadherin… 
Highly Cited
1998
Highly Cited
1998
The Epidermal Growth Factor Receptor Modulates the Interaction of E-cadherin with the Actin Cytoskeleton*
Alterations in the expression or function of molecules that affect cellular adhesion and proliferation are thought to be critical… 
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